--- product_id: 13130437 title: "II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply" brand: "k9 advantix" price: "€ 116.60" currency: EUR in_stock: true category: "K9 Advantix" url: https://www.desertcart.hr/products/13130437-ii-large-dog-vet-recommended-flea-tick-and-mosquito-treatment store_origin: HR region: Croatia --- # Protects dogs 21-55 lbs Waterproof after 24 hours Kills fleas within 12 hours II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply **Brand:** k9 advantix **Price:** € 116.60 **Availability:** ✅ In Stock ## Summary > 🐾 Stay ahead of pests—because your big pup deserves the best! ## Quick Answers - **What is this?** II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply by k9 advantix - **How much does it cost?** € 116.60 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/13130437-ii-large-dog-vet-recommended-flea-tick-and-mosquito-treatment) ## Best For - k9 advantix enthusiasts ## Why This Product - Trusted k9 advantix brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Effortless Application:** Fragrance-free, topical spot-on treatment applied in seconds—no pills or collars needed - • **No Prescription Hassle:** Available over-the-counter so your dog stays protected without delays - • **Rapid Flea Elimination:** Kills fleas within 12 hours to stop infestations fast - • **All-in-One Pest Defense:** Vet-recommended formula repels & kills fleas, ticks, mosquitoes, biting flies, and lice - • **Long-Lasting Protection:** Waterproof after 24 hours for reliable monthly defense, rain or shine ## Overview K9 Advantix II Large Dog is a vet-recommended, fragrance-free topical treatment that kills and repels fleas, ticks, mosquitoes, biting flies, and lice on dogs weighing 21-55 lbs. It starts working within 12 hours, is waterproof after 24 hours, and offers convenient monthly protection without a prescription. ## Description K9 Advantix II Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 21-55 lbs. to use K9 Advantix II Large Dog.For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park.K9 Advantix II Large Dog is a trademark of Elanco or its affiliates. ## Features - K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice - Kills fleas within 12 hours of application - Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die - Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours - No prescription needed ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B004QMX4YW | | ASIN | B004QMX4YW | | Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen | | Age Range Description | 7 weeks and older | | Allergen Information | Allergen-Free | | Best Sellers Rank | #278 in Pet Supplies ( See Top 100 in Pet Supplies ) #5 in Dog Flea Drops | | Brand Name | K9 Advantix | | Customer Reviews | 4.4 4.4 out of 5 stars (44,285) | | Date First Available | March 4, 2011 | | Department | Unisex-Adult | | Dog Breed Size | Large | | Global Trade Identification Number | 00724089203991 | | Included Components | 4 | | Is Discontinued By Manufacturer | No | | Item Form | Topical | | Item Type Name | Topical | | Item Weight | 7.94 g | | Item model number | 86315041 | | Manufacturer | Elanco US Inc | | Manufacturer | Elanco US Inc | | Manufacturer Part Number | 710546030004 | | Model Number | 86315041 | | Product Dimensions | 7.75 x 1 x 4.25 inches; 0.28 ounces | | Scent Name | Unscented | | Target Species | Dog | | UPC | 724089203991 | | Unit Count | 4 Count | | Volume | 10 Milliliters | | Warranty Description | No_warranty | ## Product Details - **Active Ingredients:** Imidacloprid, Permethrin, Pyriproxyfen - **Age Range (Description):** 7 weeks and older - **Allergen Information:** Allergen-Free - **Brand:** K9 Advantix - **Dog Breed Size:** Large - **Item Form:** Topical - **Item Volume:** 10 Milliliters - **Item Weight:** 7.94 g - **Scent:** Unscented - **Unit Count:** 4 Count ## Images ![II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply - Image 1](https://m.media-amazon.com/images/I/71U+2ITgYeL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: I am thinking about ordering a 6 pack which some would be kept for next year. How do I know what the date is on the product?** A: I looked everywhere on the individual package of the tubes and the box, there is nothing that mentions an expiration or use by date. There are phone numbers to call for questions...1-800-255-6826. Looking at how the tubes are packaged, my best guess would be that as long as they are sealed properly and not opened you could probably use unopened tubes at a later time. I have 2 dogs and ordered the six pack myself, if I don't use give my girls all 3 of their doses this year I will probably use it up next summer then. **Q: What is the expiration date on this $41 product currently for sale???** A: The expiration date is usually stamped into the package. And $41 is very good price for k9 Advantix II. It's often quite more expensive from your vet or other sites. **Q: Is this safe for sight hounds and/or dogs over the age of 12? Thank you for taking time to answer.** A: Yes, there should be no issue when using on a sight hound. I use this on my Brittney with no issues. Be advised this does not " repel" ticks. Ticks will still get onto your dog and can/will bite however, the tick will be impaired/ killed over a few hours time after biting. When used with a organic spray for Ticks you should have no issues. I have never had a flea on my dog nor my 2 cats. I recommend this product fully. Be sure to match your dog's weight with the correct Advantix. **Q: Does it send all 6 doses at a time?** A: When you order a 6 pack that means 6 doses. IF you order a 3 or 4 pack. it is that many doses respectively. ## Frequently Bought Together - K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply - K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 4-Mo Supply - K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 4-Mo Supply --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.hr/products/13130437-ii-large-dog-vet-recommended-flea-tick-and-mosquito-treatment](https://www.desertcart.hr/products/13130437-ii-large-dog-vet-recommended-flea-tick-and-mosquito-treatment) --- *Product available on Desertcart Croatia* *Store origin: HR* *Last updated: 2026-07-14*