---
product_id: 247862108
title: "Nitric Oxide Activating Anti-Aging Face Serum, 20% Vitamin C, 1 Fl Oz | Developed by Dr. Nathan S Bryan, Hydrating Serum, Minimizes Dark Spots, Promotes Smoother-Looking Skin, Reduces Fine Lines"
brand: "n1o1"
price: "€ 202.16"
currency: EUR
in_stock: true
reviews_count: 8
url: https://www.desertcart.hr/products/247862108-nitric-oxide-activating-anti-aging-face-serum-20-vitamin-c
store_origin: HR
region: Croatia
---

# Clinically proven wrinkle reduction 20% Stable Vitamin C power Hydrating Nitric Oxide boost Nitric Oxide Activating Anti-Aging Face Serum, 20% Vitamin C, 1 Fl Oz | Developed by Dr. Nathan S Bryan, Hydrating Serum, Minimizes Dark Spots, Promotes Smoother-Looking Skin, Reduces Fine Lines

**Brand:** n1o1
**Price:** € 202.16
**Availability:** ✅ In Stock

## Summary

> ✨ Unlock your skin’s youthful glow with Nobel Prize-winning science!

## Quick Answers

- **What is this?** Nitric Oxide Activating Anti-Aging Face Serum, 20% Vitamin C, 1 Fl Oz | Developed by Dr. Nathan S Bryan, Hydrating Serum, Minimizes Dark Spots, Promotes Smoother-Looking Skin, Reduces Fine Lines by n1o1
- **How much does it cost?** € 202.16 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/247862108-nitric-oxide-activating-anti-aging-face-serum-20-vitamin-c)

## Best For

- n1o1 enthusiasts

## Why This Product

- Trusted n1o1 brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Effortless Luxury Skincare:** One pump morning and night for a smooth, supple complexion that keeps you confidently camera-ready.
- • **Next-Level Hydration & Glow:** Nitric Oxide + Vitamin C combo delivers deep moisture and radiant skin without harsh chemicals.
- • **Clinically Proven Anti-Aging:** See visible wrinkle reduction and improved elasticity in just 30 days—science-backed results you can trust.
- • **Powerful Antioxidant Defense:** 20% stable Vitamin C neutralizes free radicals to brighten skin tone and minimize dark spots.
- • **Universal Skin Compatibility:** Gentle yet effective formula suits dry, oily, normal, and sensitive skin types for daily use.

## Overview

N1O1 Nitric Oxide Activating Anti-Aging Face Serum combines a groundbreaking nitric oxide formula with 20% stable Vitamin C to hydrate, brighten, and reduce fine lines. Clinically proven to improve skin elasticity and diminish wrinkles within 30 days, this serum supports collagen production and antioxidant defense for a smoother, more radiant complexion. Suitable for all skin types, it offers a clean, chemical-free solution for professional-grade anti-aging skincare.

## Description

In the realm of advanced skincare, the N1O1 Nitric Oxide Activating Serum stands out as a groundbreaking innovation, leveraging a Nobel  Prize-winning discovery to target the underlying causes of aging skin, such as wrinkles, loss of elasticity, and skin damage.
This serum,  supported by robust clinical trials, marks a revolutionary approach to skincare by harnessing the power of nitric oxide to revitalize and rejuvenate the skin. Within a mere 30 days, users can witness a significant reduction in the appearance of wrinkles, thanks to the serum's ability to enhance skin elasticity and smoothness. As the first age-defying product of its kind, it offers a unique solution to those seeking to maintain a youthful and vibrant skin appearance without resorting to invasive procedures.
The serum's benefits are multifaceted, extending beyond simple wrinkle reduction. It actively stimulates collagen production, crucial for maintaining skin's firmness and preventing sagging. Additionally, it enhances the flow of oxygen, hydration, and essential nutrients directly to skin cells, effectively improving skin tone, texture, and overall appearance.
The N1O1 activating serum is formulated with a blend of powerful ingredients, including water, ascorbic acid, polysorbate 20,  sodium nitrite, and a potent 20% concentration of Vitamin C. This composition works synergistically to shield skin from oxidative stress by neutralizing free radicals, thus preventing further cellular damage and maintaining skin's vibrancy and resilience.
Incorporating this serum into one's skincare routine is effortless and promises to yield visible results with consistent use. Each bottle contains enough product for up to 70 applications, ensuring a long-lasting supply. The application involves a simple process of mixing a single pump from each chamber and applying it to the face and neck,  ensuring that it fully absorbs before proceeding with any additional skincare products. Recommended for use both morning and night, this regimen ensures that the skin is continuously nourished, benefiting from the revolutionary anti-aging properties of Nitric Oxide. By addressing aging at the cellular level, the N1O1 Serum not only diminishes existing signs of aging but also provides a proactive approach to preserving skin's natural beauty and resilience over time.

## Features

- Hydrating And Moisturizing: Our moisturizing face serum combines Nitric Oxide with Vitamin C to bring you a facial serum that will help support smooth, supple and soft skin without relying on any harsh chemicals or additives for day to day skincare
- Brighter And Smoother Skin: Our facial skin care serum with Nitric Oxide helps support collagen, hydration, and nutrient flow to your skin to help reduce the visibility of fine lines, dark spots, and other signs of aging without relying on any harsh chemicals or additives
- Even Skin Tone Support: This skin brightening serum contains 20% stable Vitamin C that not only helps moisturize the skin but also helps provide antioxidant support to help reduce oxidative stress by helping neutralize free-radicals to support an even and brighter skin tone
- Suitable For All Skin Types: The vitamin C face serum utilizes Nitric Oxide along with a balanced formula to help support the skin without relying on any harsh chemicals. This nitric oxide and Vitamin C serum is suitable for dry, oily, normal, and sensitive skin to offer gentle support
- Simple To Use: Each bottle of activating serum can provide up to a 30 day supply. Simply apply a single pump of serum to your palm, gently massage it onto your face and neck, and let it rest for 1-2 minutes. Our vitamin C serum can be applied both during the day and night

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Asin | B08LNTJZST |
| Best Sellers Rank | #1,028 in Facial Serums |
| Item Model Number | n1o1 |
| Manufacturer | Pneuma Nitric Oxide |
| Product Dimensions | 6 x 2 x 2 inches; 3.53 ounces |
| Upc | 608597658903 |

## Product Details

- **Product Benefits:** Anti-Aging
- **Scent:** Fragrance Free
- **Skin Type:** All
- **Special Ingredients:** Antioxidants, Vitamin C, Vitamin E
- **Use for:** Face

## Images

![Nitric Oxide Activating Anti-Aging Face Serum, 20% Vitamin C, 1 Fl Oz | Developed by Dr. Nathan S Bryan, Hydrating Serum, Minimizes Dark Spots, Promotes Smoother-Looking Skin, Reduces Fine Lines - Image 1](https://m.media-amazon.com/images/I/519vaxPub-L.jpg)

## Questions & Answers

**Q: What color is the serum supposed to be directly out of the bottle?**
A: The bottle is a dual chamber system - one side of the bottle contains vitamin C, the other side contains liquid nitric oxide.  When you use one pump from each side of the bottle, and mix the drops together in the palm of your hand, the vitamin C acts as the activating ingredient to activate the nitric oxide.  The nitric oxide serum is clear, the vitamin C can be an amber color.

**Q: Should I use hyaluronic acid in addition to this, or does this replace hyaluronic acid?**
A: Thank you for reaching out!  You should use Hyaluronic Acid after using our Nitric Oxide Activating Serum.  The serum help with the absorption of the HA...and will actually boost it!  Hope this helps!

**Q: What percentage of nitric oxide?**
A: Thank you for asking!  The serum is a dual chamber bottle that contains nitrite in one chamber and Vitamin C in the other.  The vitamin C is the activating agent which when mixed with the nitrite creates nitric oxide gas.  The mixture is 100% nitric oxide.  Hope this helps.

**Q: is it animal tested?**
A: No, our products are never animal tested.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Removed my scar, despite infrequent use
*by  on Reviewed in the United States August 26, 2025*

Three years ago, I cut my face right in between my eyebrows. I got left with a 1/4” scar that ran deep, extended my wrinkle and gave me a permanently worried look.It got worse over time. My trusty moisturizer helped everywhere, except for the scar. The need to do something overcame my skepticism about nitric oxide, so I decided to give it a chance. I had no expectations.The instructions recommend daily application. I applied about twice a week. For a couple weeks, there was no change. Maybe a month later I noticed the scar is no longer joined to my eyebrow wrinkle, reducing my angry, worried look.I began applying every other day and after a few more weeks, the scar is now flat and only visible within a few feet distance. By flat I mean no longer deep, almost completely flush with the skin, with a very slightly discolored center.The scar basically shrank in size and almost disappeared optically. My wrinkles also improved substantially.I now believe that the scar will disappear completely with another few weeks of frequent use. I started to apply all over my face and neck, since the minimum dose is large enough.I’m now administering to whoever asks: seniors, youth, children, … whoever has skin damage.The cream itself clogs pores a little so I shower it off at the end of the day. It’s not suitable for wearing light colors as it can stain them yellow. I wish it came in glass instead of plastic.I thought I’d keep my scar for the rest of my life, looking progressively angrier as I age. And yet, here we are - I’ve reversed three years of skin damage.Thank you Dr. Nathan Bryer!

### ⭐⭐⭐⭐⭐ It’s worth the $100
*by  on Reviewed in the United States May 15, 2026*

I was having horrible skin months, maybe years, red blotchy broken out, dry patches I kept digging at it and it refused to heal or retain moisture. My 30’s were mixed skin but my 40’s were just bad, bag on head horrendous.I bought it on a Sat same day delivery. I’m shocked, near 6 days later I’m writing a review. The dry patches are gone. The breakouts gone. The redness and scars are slower to respond but, I think eventually that will fade as well. If I can ditch makeup I’d call this a complete game changer.My skin did lightly flush initially but it goes away quickly for me.I’m excited to see what a month out looks like.These pictures are a 7 days using the serum post wash twice a day followed by my normal moisturizer. Maintaining my makeup routine.This comes highly recommended by me!

### ⭐⭐⭐⭐⭐ It works!
*by  on Reviewed in the United States April 4, 2023*

This is my no. 1 go-to serum. I have been using it since 2021 and have seen a great improvement in the smoothness of my skin, particularly around my eyes. One morning in 2021, I looked in the mirror and it was like somebody pulled a switch. The delicate skin around the eyes, that had been fairly smooth, suddenly sagged and looked baggy. None of my existing products did anything. Fortunately, I saw a TV commercial for the N1O1 serum and decided to give it a try. Since I am a woman of a certain age, I followed the instructions and began using it twice a day, with emphasis on the eye area. I have sensitive skin around the eyes and on the cheeks. There was, and still is, no irritation. Within about 3 days, there was improvement. The skin looked much more lifted. The whole eye area began to smooth out. In fact, since I was applying the serum over my whole face, my facial skin began to look smoother. Pores looked smaller, and the skin tone was more even. The effect of the serum seems to build over time. I continue to use the serum every day and am very pleased with the results.

## Frequently Bought Together

- Nitric Oxide Activating Serum with Antioxidants | Hydrating Serum For Face | Decreases Wrinkles | Pore Minimizer | Improves Skin Texture | Helps Dark Spots | 1 Fl Oz, 30ml
- N1O1 Nitric Oxide Lozenges - 60 Count - Nitric Oxide Supplement for Heart Health, Circulation, Energy, Blood Flow, Oxygenation, Healthy Blood Pressure, Cardiovascular Support for Men & Women
- N1O1 Moisturizer Face Cream - Day & Night Face Moisturizer with Nitric Oxide, Peptide Complex, Epidermal Growth Factor - Tightening & Firming Skin Care Products for Wrinkles, Dark Spots - 1.75 oz.

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*Product available on Desertcart Croatia*
*Store origin: HR*
*Last updated: 2026-08-02*