--- product_id: 254550393 title: "Life Extension Optimized Folate L-Methylfola 1000 Mcg Vegetarian Tablets, 100 Count" brand: "life extension" price: "€ 46.54" currency: EUR in_stock: true reviews_count: 5 category: "Life Extension" url: https://www.desertcart.hr/products/254550393-life-extension-optimized-folate-l-methylfola-1000-mcg-vegetarian-tablets store_origin: HR region: Croatia --- # 100% vegetarian formula 1000 mcg bioactive 5-MTHF per tablet Supports healthy homocysteine & cardiovascular function Life Extension Optimized Folate L-Methylfola 1000 Mcg Vegetarian Tablets, 100 Count **Brand:** life extension **Price:** € 46.54 **Availability:** ✅ In Stock ## Summary > 💡 Elevate your wellness game with the folate upgrade your body actually absorbs! ## Quick Answers - **What is this?** Life Extension Optimized Folate L-Methylfola 1000 Mcg Vegetarian Tablets, 100 Count by life extension - **How much does it cost?** € 46.54 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/254550393-life-extension-optimized-folate-l-methylfola-1000-mcg-vegetarian-tablets) ## Best For - life extension enthusiasts ## Why This Product - Trusted life extension brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Trusted & Proven:** Highly rated with real-life transformative reviews—experience the difference beyond prescriptions - • **Vegetarian & Clean:** Pure vegetarian tablets with no artificial fillers, perfect for mindful wellness seekers - • **Heart & Mind Synergy:** Clinically supports cardiovascular health and neurotransmitter synthesis for cognitive edge - • **Genetic Metabolism Friendly:** Ideal for those with genetic folate absorption challenges—don’t settle for less - • **Ultra-Bioavailable Folate Power:** Delivers 5,000 mcg of 5-MTHF, up to 7x more absorbable than folic acid ## Overview Life Extension Optimized Folate L-Methylfolate 1000 mcg Vegetarian Tablets provide a potent, bioactive form of folate (5-MTHF) that supports cardiovascular health, neurotransmitter synthesis, and healthy homocysteine levels. Designed for adults with absorption challenges, these vegetarian tablets deliver superior bioavailability—up to 7 times more effective than standard folic acid—backed by compelling user testimonials and trusted by health-conscious professionals. ## Description Is High Potency Optimized Folate the right supplement for your nervous system health? Folate helps maintain homocysteine levels within the normal range, which promotes cardiovascular health. And it also supports neurotransmitter synthesis - which in turn helps maintain cognitive abilities. However, not everyone has sufficient activity of the enzyme required to convert folate to its biologically active form, 5-methyltetrahydrofolate, or 5-MTHF. That's why each vegetarian tablet of High Potency Optimized Folate provides 5,000 mcg of the bioactive 5-MTHF form of folate which is up to 7 times more bioavailable than ordinary folic acid. Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By depleting excess homocysteine, folate benefits cardiovascular health and nervous system function. Review: FABULOUS!! Life changing for a member of my family. AND, this worked better than the prescription methylfolate. The LE is bound to a glucosamine while the Rx is bound to calcium. I do not understand why this works better than the Rx but perhaps the calcium vs. glucosamine is the reason. If you have the genetic inability to absorb folic acid this is THE answer. I am shocked at how quickly my family members life changed as a result of this supplement. She started by taking 15 a day (to make it equivalent to the Rx) and within a day or two I couldn't believe the difference. Within a week she was a new person! It was unbelievable!! Then she ran out of the supplement....day one she could not walk easily, day two she could not speak properly or understand those around her, day 3 she could hardly move. She ran out and filled the Rx as she could not find this product in her small town. She anxiously took the Rx waiting for the same miracle to occur. Day 1, not much improved, day 2 - minor improvements, day 3 - daunting realization that the LE product is better than the Rx, day 4 - overnighted the LE product to her home, day 5 - took both the supplement and Rx. She began a downward spiral. CONCLUSION: the LE supplement is BETTER than the Rx for her and the Rx interferes with absorption of the supplement. This is just her experience and everyone is different but I wanted to share this story as the pharmacists were all telling her the Rx was better and all the supplements were the same. She has since tried other supplements and they are not as effective. If you think you have the genetic inability to metabolize folic acid try this. As a result of her dramatic turn around her doctor is now aggressively appealing the rejection she received from her insurance company for the genetic test. Do not wait for doctors and insurance companies to make/break your life! Her symptoms (which are now gone) included: non-existent short term memory, ADD, anxiety, extreme fatigue, muscle weakness, falling, impulsiveness, inability to follow through on anything, and much more. She had been diagnosed with EVERYTHING except the actual disease. Yea, Life Extension. We love you!! Review: Theory has it that some people can't process Vitamin D correctly - and that this is the stuff they need. It's supposed to help with depression. I'm not certain if it is....but they are small tablets that have no discernible nasty smell or taste (unlike a lot of other vitamins) so it's well worth a try! Quick service too! ## Features - Supports cardiovascular health - Supports neurotransmitter synthesis and critical enzyme reactions - Maintains healthy homocysteine levels ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B005CD3KCA | | ASIN | B005CD3KCA | | Age Range Description | Adult | | Best Sellers Rank | #66,242 in Health ( See Top 100 in Health ) #641 in Vitamin B Supplements | | Brand | Life Extension | | Customer Reviews | 3.9 3.9 out of 5 stars (57) | | Customer reviews | 3.9 3.9 out of 5 stars (57) | | Date First Available | 8 August 2012 | | Format | Tablet | | Is Discontinued By Manufacturer | No | | Item model number | 1939 | | Manufacturer | Life Extension | | Product Dimensions | 5.08 x 5.08 x 8.89 cm; 49.9 g | | Units | 100 Count | | Weight | 26 Grams | ## Product Details - **Brand:** Life Extension - **Diet type:** Vegetarian - **Flavour:** Unflavored - **Item form:** Tablet - **Product benefits:** cardiovascular health ## Images ![Life Extension Optimized Folate L-Methylfola 1000 Mcg Vegetarian Tablets, 100 Count - Image 1](https://m.media-amazon.com/images/I/61nElxorc+L.jpg) ## Customer Reviews ### ⭐⭐⭐⭐⭐ Review *by L***. on 4 June 2015* FABULOUS!! Life changing for a member of my family. AND, this worked better than the prescription methylfolate. The LE is bound to a glucosamine while the Rx is bound to calcium. I do not understand why this works better than the Rx but perhaps the calcium vs. glucosamine is the reason. If you have the genetic inability to absorb folic acid this is THE answer. I am shocked at how quickly my family members life changed as a result of this supplement. She started by taking 15 a day (to make it equivalent to the Rx) and within a day or two I couldn't believe the difference. Within a week she was a new person! It was unbelievable!! Then she ran out of the supplement....day one she could not walk easily, day two she could not speak properly or understand those around her, day 3 she could hardly move. She ran out and filled the Rx as she could not find this product in her small town. She anxiously took the Rx waiting for the same miracle to occur. Day 1, not much improved, day 2 - minor improvements, day 3 - daunting realization that the LE product is better than the Rx, day 4 - overnighted the LE product to her home, day 5 - took both the supplement and Rx. She began a downward spiral. CONCLUSION: the LE supplement is BETTER than the Rx for her and the Rx interferes with absorption of the supplement. This is just her experience and everyone is different but I wanted to share this story as the pharmacists were all telling her the Rx was better and all the supplements were the same. She has since tried other supplements and they are not as effective. If you think you have the genetic inability to metabolize folic acid try this. As a result of her dramatic turn around her doctor is now aggressively appealing the rejection she received from her insurance company for the genetic test. Do not wait for doctors and insurance companies to make/break your life! Her symptoms (which are now gone) included: non-existent short term memory, ADD, anxiety, extreme fatigue, muscle weakness, falling, impulsiveness, inability to follow through on anything, and much more. She had been diagnosed with EVERYTHING except the actual disease. Yea, Life Extension. We love you!! ### ⭐⭐⭐⭐ Review *by P***H on 16 February 2017* Theory has it that some people can't process Vitamin D correctly - and that this is the stuff they need. It's supposed to help with depression. I'm not certain if it is....but they are small tablets that have no discernible nasty smell or taste (unlike a lot of other vitamins) so it's well worth a try! Quick service too! ### ⭐⭐⭐⭐⭐ Review *by C***C on 25 March 2016* Much more effective in addressing MTHFR symptoms than any other form of folate I've tried. I believe I've trialed each of the forms currently available in the US and effects ranged from no change to making me sicker than before. The only prescription form of folate currently available, Deplin, resulted in the worst increase in symptoms. There are multiple forms of folate. Yet as it stands now, single large pharmaceutical company holding the monopoly on "prescription folate" [essentially a naturally occurring substance, which to the best of my understanding they have notcontributed to the development of in the slightest] is opting to produce one form only, using cheaper ingredients than most of the the nonprescription forms. So I guess let's hope fellow MTHFRs, that they don't go after life extensions right to make this form. Good luck on your quest for better health. ## Frequently Bought Together - Life Extension Optimized Folate L-Methylfola 1000 Mcg Vegetarian Tablets, 100 Count - Life Extension Bioactive Complete B-Complex, Heart, Brain and Nerve Support, Healthy Energy, Metabolism, Complete B Complex, 60 Vegetarian Capsules - Life Extension Vitamins D and K with Sea-Iodine – Bone, Brain, Thyroid & Arterial Support – Non-GMO, Once Daily, Gluten-Free – 60 Capsules --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.hr/products/254550393-life-extension-optimized-folate-l-methylfola-1000-mcg-vegetarian-tablets](https://www.desertcart.hr/products/254550393-life-extension-optimized-folate-l-methylfola-1000-mcg-vegetarian-tablets) --- *Product available on Desertcart Croatia* *Store origin: HR* *Last updated: 2026-05-16*