--- product_id: 3999959 title: "Nutramax Denosyl Liver & Brain Supplement for Large Dogs, Tablets, 30ct | Brain & Liver Support for Dogs with S-Adenosylmethionine (SAMe), For Dogs Over 34 lbs, Stabilized Tablets" brand: "nutramax laboratories" price: "€ 116.14" currency: EUR in_stock: true reviews_count: 10 url: https://www.desertcart.hr/products/3999959-nutramax-denosyl-liver-and-brain-supplement-for-large-dogs-tablets store_origin: HR region: Croatia --- # Formulated for large dogs 34+ lbs Supports cognitive function Boosts antioxidant glutathione Nutramax Denosyl Liver & Brain Supplement for Large Dogs, Tablets, 30ct | Brain & Liver Support for Dogs with S-Adenosylmethionine (SAMe), For Dogs Over 34 lbs, Stabilized Tablets **Brand:** nutramax laboratories **Price:** € 116.14 **Availability:** ✅ In Stock ## Summary > 🐾 Elevate your dog’s vitality—brain and liver in perfect harmony! ## Quick Answers - **What is this?** Nutramax Denosyl Liver & Brain Supplement for Large Dogs, Tablets, 30ct | Brain & Liver Support for Dogs with S-Adenosylmethionine (SAMe), For Dogs Over 34 lbs, Stabilized Tablets by nutramax laboratories - **How much does it cost?** € 116.14 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/3999959-nutramax-denosyl-liver-and-brain-supplement-for-large-dogs-tablets) ## Best For - nutramax laboratories enthusiasts ## Why This Product - Trusted nutramax laboratories brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Vet-Trusted Quality:** From the #1 vet-recommended supplement brand for 30+ years - • **Optimized Absorption:** Enteric-coated tablets ensure maximum nutrient delivery - • **Brain Boosting Formula:** Clinically shown to support cognitive health in aging dogs - • **Liver Detox Powerhouse:** SAMe boosts glutathione, your dog's natural detox shield - • **Tailored for Large Dogs:** Specifically designed dosage for dogs over 34 lbs ## Overview Nutramax Denosyl is a scientifically backed supplement featuring stabilized SAMe tablets designed for large dogs (34+ lbs). It supports liver detoxification by enhancing glutathione production and promotes cognitive health. Trusted by veterinarians for over 30 years, Denosyl offers enteric-coated tablets for optimal absorption, ensuring your dog’s vital organs get premium care. ## Description Denosyl contains SAMe (s-adenosylmethionine) to help support the liver health of dogs and may support brain health. It is available in enteric-coated tablets. Denosyl Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements. ## Features - High-Quality Ingredients: Denosyl for small dogs and cats contains S-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione - one of the liver's main detoxifying agents - Support Your Pet's Liver Health: The liver, one of your pet's most vital organs, is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system - Cognitive Support: While best known for supporting the liver in dogs, research has shown that the SAMe in Denosyl may help support cognitive function in dogs and cats - Exceptional Quality: Denosyl is backed by science and undergoes thorough quality inspections to ensure your dog receives a safe, high-quality product - From the #1 Veterinarian Recommended Supplement Company: Nutramax has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, skin and coat health, calming, and more - Convenient Tablet Form: Each bottle contains 30 stabilized, enteric-coated tablets designed specifically for large dogs to ensure optimal absorption and effectiveness - Antioxidant Support: SAMe helps boost glutathione production, providing powerful antioxidant protection to support your dog's overall cellular health and detoxification processes ## Technical Specifications | Specification | Value | |---------------|-------| | Asin | B000RI3N1S | | Best Sellers Rank | #310 in Dog Hip & Joint Care | | Date First Available | December 21, 2007 | | Item Model Number | DENO425MG | | Manufacturer | Nutramax | ## Product Details - **Active Ingredients:** S-Adenosylmethionine 425 mg - **Brand:** Nutramax Laboratories - **Flavor:** Other - **Item Form:** Tablet - **Item Weight:** 1.6 Ounces ## Images ![Nutramax Denosyl Liver & Brain Supplement for Large Dogs, Tablets, 30ct | Brain & Liver Support for Dogs with S-Adenosylmethionine (SAMe), For Dogs Over 34 lbs, Stabilized Tablets - Image 1](https://m.media-amazon.com/images/I/61MM2OQOz6L.jpg) ![Nutramax Denosyl Liver & Brain Supplement for Large Dogs, Tablets, 30ct | Brain & Liver Support for Dogs with S-Adenosylmethionine (SAMe), For Dogs Over 34 lbs, Stabilized Tablets - Image 2](https://m.media-amazon.com/images/I/81CnYSEAiYL.jpg) ![Nutramax Denosyl Liver & Brain Supplement for Large Dogs, Tablets, 30ct | Brain & Liver Support for Dogs with S-Adenosylmethionine (SAMe), For Dogs Over 34 lbs, Stabilized Tablets - Image 3](https://m.media-amazon.com/images/I/81IiCGsVd5L.jpg) ![Nutramax Denosyl Liver & Brain Supplement for Large Dogs, Tablets, 30ct | Brain & Liver Support for Dogs with S-Adenosylmethionine (SAMe), For Dogs Over 34 lbs, Stabilized Tablets - Image 4](https://m.media-amazon.com/images/I/61N9QfiYHuL.jpg) ![Nutramax Denosyl Liver & Brain Supplement for Large Dogs, Tablets, 30ct | Brain & Liver Support for Dogs with S-Adenosylmethionine (SAMe), For Dogs Over 34 lbs, Stabilized Tablets - Image 5](https://m.media-amazon.com/images/I/918-I+xKNaL.jpg) ## Available Options This product comes in different **Size, Item Package Quantity** options. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Please buy this for your dog! Great for Cognitive issues and liver! *by on Reviewed in the United States December 28, 2025* Currently waiting on 2 more packs of these! I ran out 2 days ago and my girl is getting anxious again. She has slightly elevated liver enzymes but I started her on this for cognitive issues.She is still listening to commands and doesn't get lost but her night time anxiety and barking has increased now that she is almost 11.This girl has been through everything medically. Her bloodwork, urine and stool samples are all flawless other than the slight elevated liver levels.We have been fighting symptoms for 2 months and THIS supplement got her back to 100%. She is seriously so sharp now!I will keep her on these for life. Just seeing what day 2 without them is like.She's not bad, but her normal routine is being disturbed by her barking and pacing. It should be here within an hour. I almost guarantee she will be back to normal by tomorrow.I gave her all her meds (even extra cbd). The only thing she has missed is this med and she is more irritable/anxious. I seriously can't wait to get these in.I give them afternoon after we get home from work, on an empty stomach and 2 hours before dinner. She is on a probiotic and pumpkin, so no stomach upset.Put it in a pill pocket if they wont take it! Once it started helping her, she takes it with no problem. She wants to take it! Thank you for making a supplement that WORKS! ### ⭐⭐⭐⭐⭐ Just what doctor ordered & better priced!! *by on Reviewed in the United States January 31, 2026* Just what the doctor ordered! And cheaper than purchasing it at the vet's office! ### ⭐⭐⭐⭐⭐ If her levels had been higher I would have given it to her every day like recommended. The vet told me that the Denosyl ... *by on Reviewed in the United States December 26, 2016* I have a 12 year old Siberian Husky. Ever since she was about 6 years old, I have had a full blood panel run on her once a year. This past June for the first time ever she had a slightly elevated liver level. It was 198. The year before it was 155. The vet wasn't too concerned as it was only slightly elevated. He said that I could start giving her Denosyl. The price at the vet was $85.00 for 30 pills. I fount it here on Amazon for $50. I started giving it to here in July or August. I have been giving it to for about 4 months. I probably give it to her about 4 days a week. Since her levels were only slightly elevated I figured it was okay if I missed a few days a week. I also give her Metacam daily for arthritis that she has had since she was a puppy. I have 4 Siberian Huskies and it obviously gets expensive caring for all of them, so it saves a little money not giving it to her everyday. I took her this week to have another blood panel run. It has been 6 months since the last blood work in June 2016. Her Liver level dropped from 198 to 142! It is now lower than it was a year and half ago when I tested her in June 2015 and it was 155 and was still considered normal. I am thrilled with the results of this in only 4 months giving it to her everyother day. If her levels had been higher I would have given it to her every day like recommended. The vet told me that the Denosyl must be working and that I can still give it to her everyother day if I would like. I will definitely continue giving this product to my dog. I am thrilled with the results in just 4 short months. ## Frequently Bought Together - Nutramax Laboratories Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe), 30 Tablets - Greenies Pill Pockets for Dogs Large Size, Soft Dog Treats, with Real Peanut Butter, 15.8 oz. Pouch (60 Treats) - Greenies Pill Pockets for Dogs Large Size, Soft Dog Treats, Chicken Flavor, 15.8 oz. Pouch (60 Treats) --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.hr/products/3999959-nutramax-denosyl-liver-and-brain-supplement-for-large-dogs-tablets](https://www.desertcart.hr/products/3999959-nutramax-denosyl-liver-and-brain-supplement-for-large-dogs-tablets) --- *Product available on Desertcart Croatia* *Store origin: HR* *Last updated: 2026-08-09*