--- product_id: 4303283 title: "Advantage II Extra Large Dog" brand: "advantage" price: "€ 102.87" currency: EUR in_stock: true category: "Advantage" url: https://www.desertcart.hr/products/4303283-advantage-ii-extra-large-dog store_origin: HR region: Croatia --- # For dogs 55+ lbs Waterproof after 24 hrs Kills fleas in 12 hrs Advantage II Extra Large Dog **Brand:** advantage **Price:** € 102.87 **Availability:** ✅ In Stock ## Summary > 🐾 Stay ahead of fleas—because your big dog deserves big protection! ## Quick Answers - **What is this?** Advantage II Extra Large Dog by advantage - **How much does it cost?** € 102.87 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/4303283-advantage-ii-extra-large-dog) ## Best For - advantage enthusiasts ## Why This Product - Trusted advantage brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Rapid Action Formula:** Eliminates adult fleas, larvae, and eggs within 12 hours. - • **Waterproof & Durable:** Resists water after 24 hours so your dog stays protected rain or shine. - • **Month-Long Protection:** Keeps working for 30 days to break the flea life cycle. - • **Effortless Application:** Topical, no prescription needed, and fragrance-free for easy use. - • **Vet-Recommended Flea Defense:** Trusted by professionals for large dogs over 55 lbs. ## Overview Advantage II XL is a vet-recommended, topical flea treatment designed for dogs over 55 lbs. It kills fleas at all life stages within 12 hours and provides 30 days of continuous protection. The fragrance-free, waterproof formula is easy to apply without a prescription, ensuring your dog stays comfortable and flea-free all month long. ## Description Product Description Advantage II Extra Large Dog is the vet-recommended prevention and treatment of flea and lice infestations in dogs. Advantage II Extra Large Dog flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your dog or puppy. In fact, within 12 hours of application, Advantage II Extra Large Dog topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your dog to die.This 30-day treatment effectively breaks the flea life cycle, controlling existing flea and lice infestations and preventing further infestations all month long. Fleas not only cause discomfort; they can also pose other health risks. Monthly use of Advantage II Extra Large Dog is important to protect your dog against fleas that may cause transmission of tapeworms in dogs, Flea Allergy Dermatitis and flea bite anemia.That’s why Advantage II topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that Advantage II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. Advantage II Extra Large Dog flea and lice protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use Advantage II Extra Large Dog.For the ultimate convenience in care, Advantage II Extra Large Dog is available over the counter – no prescription needed. And, you can stock up with a subscription for regular doorstep deliveries so you never miss a monthly treatment. Once Advantage II Extra Large Dog is applied, your dog is ready to get right back to exploring his favorite places – from the backyard to the dog park.Advantage II Extra Large Dog is a trademark of Elanco or its affiliates. Brand Story By Advantage ## Features - Vet recommended flea treatment and prevention for dogs at weighing over 55 lbs., at least 7 weeks of age - Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment - Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days - Easy-to-apply topical treatment, no prescription needed - Fragrance-free formula, waterproof after 24 hours ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B004QBL9IQ | | ASIN | B004QBL9IQ | | Active Ingredients | Imidacloprid, Pyriproxyfen | | Age Range Description | 7 weeks and older | | Allergen Information | Allergen-Free | | Best Sellers Rank | #1,476 in Pet Supplies ( See Top 100 in Pet Supplies ) #15 in Dog Flea Drops | | Brand Name | Advantage | | Customer Reviews | 4.5 4.5 out of 5 stars (19,207) | | Date First Available | July 15, 2004 | | Department | Unisex-Adult | | Dog Breed Size | Large | | Global Trade Identification Number | 00724089203052, 00724089617743, 10724089366341 | | Is Discontinued By Manufacturer | No | | Item Form | Topical | | Item Type Name | Topical | | Item Weight | 0.1 Pounds | | Item model number | 81520305 | | Manufacturer | Elanco US Inc | | Manufacturer | Elanco US Inc | | Manufacturer Part Number | 86336634 | | Manufacturer recommended age | 1 month and up | | Model Number | 81520305 | | Product Dimensions | 6.5 x 1 x 4.25 inches; 1.6 ounces | | Scent Name | Unscented | | Target Species | Dog | | UPC | 724089617743 724089203052 | | Unit Count | 4 Count | | Volume | 16 Milliliters | ## Product Details - **Active Ingredients:** Imidacloprid, Pyriproxyfen - **Age Range (Description):** 7 weeks and older - **Allergen Information:** Allergen-Free - **Brand:** Advantage - **Dog Breed Size:** Large - **Item Form:** Topical - **Item Volume:** 16 Milliliters - **Item Weight:** 0.1 Pounds - **Scent:** Unscented - **Unit Count:** 4 Count ## Images ![Advantage II Extra Large Dog - Image 1](https://m.media-amazon.com/images/I/71GKQMZnBWL.jpg) ## Available Options This product comes in different **Size, Style** options. ## Questions & Answers **Q: I have always used Advantage on dogs AND cats. Advantage II now says not to use on cats. Anybody know what changed?** A: Be a bit weary of "they have the same ingredients" argument, yes they do have the same percentage of ingredients but those ingredients may not be mixed homogeneously, meaning if you divvy it up you may get a larger percentage of ingredient over another. When you use the appropriate sized cat/dog vial all of what's in that vial gets put on your pet, so 9% of one ingredient, 1% of another 90% of "other" each and every time in the correct proportions, if for whatever reason the stuff is layered in the tube and you use a syringe to pull out 1/10th you could get 0% to 90% by volume of that ingredient that is "9%" depending upon how well mixed up it is, and Bayer really has no need to mix things up since they are packaging a product intended to use all of it in one shot. So if you use the dog version on cats do try to mix up the stuff in some way, shake the tube, pour it into a smaller container and mix, etc, which in itself is no guarantee things will be mixed evenly, but it's better than nothing. **Q: can you still bathe your dog after using?** A: My vets told me I was told not to bathe 2 days before and after. I had bathed my dog the same day, and though he was totally dry before application, He had no flea control at all a a result. . **Q: How many ml difference in amount for each of the sizes? like, how much per tube. for 10lb and under, large dog, extra large dog etc.** A: Apparently the amount used on a dog doesn't matter much. I took a new dog to the vet for shots and he applied Advantix II without my knowing it, I said "I had just put it on him" and he said "it doesn't matter, it won't hurt him" and it didn't. **Q: Is this for ticks too?** A: No. You will want to purchase K9 Advantix. That will kill fleas and ticks. ## Frequently Bought Together - Advantage II XL Dog Vet-Recommended Flea Treatment & Prevention | Dogs Over 55 lbs. | 4-Month Supply - Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 4-Month Supply - Advantage II Large Dog Vet-Recommended Flea Treatment & Prevention | Dogs 21-55 lbs. | 4-Month Supply --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.hr/products/4303283-advantage-ii-extra-large-dog](https://www.desertcart.hr/products/4303283-advantage-ii-extra-large-dog) --- *Product available on Desertcart Croatia* *Store origin: HR* *Last updated: 2026-07-14*