--- product_id: 49917744 title: "E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested" brand: "e45" price: "€ 49.02" currency: EUR in_stock: true reviews_count: 13 category: "E45" url: https://www.desertcart.hr/products/49917744-e45-itch-relief-cream-500g-for-eczema-dry-skin-dermatitis store_origin: HR region: Croatia --- # 24h hydration with 5% urea Perfume-free, non-greasy formula Dual-action anti-itch & irritation relief E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested **Brand:** e45 **Price:** € 49.02 **Availability:** ✅ In Stock ## Summary > ✨ Say goodbye to itchy skin drama with E45’s soothing power! 🛡️ ## Quick Answers - **What is this?** E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested by e45 - **How much does it cost?** € 49.02 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/49917744-e45-itch-relief-cream-500g-for-eczema-dry-skin-dermatitis) ## Best For - e45 enthusiasts ## Why This Product - Trusted e45 brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Gentle for Every Skin:** Perfume-free, dermatologically tested, safe for adults and infants 1+ month. - • **Soothe Itch Instantly:** Powerful lauromacrogols target and calm itching from eczema, dermatitis, and dry skin. - • **Effortless Application:** Convenient pump dispenser delivers precise 4g doses for mess-free twice daily use. - • **Hydrate & Heal All Day:** Locks in moisture for 24-hour skin comfort with clinically proven 5% urea. - • **Trusted Legacy Skincare:** 60 years of expert formulation trusted by millions for dry, irritated skin relief. ## Overview E45 Itch Relief Cream is a dermatologist-tested, dual-action treatment formulated with 5% urea and lauromacrogols to provide 24-hour hydration and effective relief from itching caused by eczema, dermatitis, and dry skin. Its non-greasy, perfume-free formula is safe for all skin types, including infants over 1 month, and comes in a convenient 500g pump bottle for easy, precise application. ## Description Product Description E45 Itch Relief Cream contains an anti-itch ingredient, lauromacrogols, which treats and soothes the itching caused by eczema, dermatitis, pruritus and scaling skin conditions. Formulated with urea, a moisturiser found naturally within the skin, E45 Itch Relief Cream is non-greasy, moisturising and can soothe the skin and leave it feeling calm and comfortable. RB-M-01759. Ingredients Dimeticone, Phenyl Dimeticone, Liquid Paraffin, Cetyl Palmitate, Stearic Palmitic Acid, Octyldodecanol, Glycerol, Polysorbate, Carbomer, Trometamol, Benzyl Alcohol, Purified Water. Directions Twist pump to open position, depress pump to dispense cream, twist back to lock, apply to the affected skin 2 times daily, if symptoms persist, consult your doctor, each use of the pump dispenses approx 4 g of cream, E45 Itch Relief Cream for pruritus, eczema, dermatitis, and scaling skin conditions, always read the label Box Contains 1 X E45 Itch Relief Cream - 500 g Review: Works well - Really works well make sure you choose the correct product, cream not the cheaper lotion which is a good moisturiser but does nothing for itchy backs. Good dispenser Review: Does a good job - Very cooling and comforting when applied to my itchy skin. Much more effective than itch relieving shower soap for me. ## Features - TREAT ITCHING AND SKIN IRRITATION – E45 Itch Relief Cream is a dual action treatment for skin irritation and itching caused by dry skin conditions, eczema, dermatitis, pruritus, and scaling skin conditions - MOISTURISING AND ANTI-ITCH INGREDIENTS – E45 Itch Relief Cream is formulated with urea which helps your skin to retain moisturise and keeps it hydrated. Our cream is also dermatologically tested to provide effective relief for itchy skin - HOW TO USE – Apply to the affected skin area twice daily for effective relief for itching and skin irritation. Our cream is perfume free and can be used in all skin areas, body, face, and hands. Suitable for adults and infants over the age of 1 month - QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. It has proven dermatological expertise dedicated to vulnerable dry skin - HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 our cream was introduced to pharmacy and retail in 1980 ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B001EJOHUU | | Active Ingredients | urea | | Active ingredients | urea | | Age Range Description | Adult | | Age range (description) | Adult | | Benefits | Soothing | | Best Sellers Rank | 517 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 12 in Itching & Rash Treatments | | Brand | E45 | | Brand Name | E45 | | Container Type | Bottle | | Country as Labeled | United Kingdom | | Customer Reviews | 4.6 out of 5 stars 3,342 Reviews | | Item Dimensions | 50 x 50 x 240 millimetres | | Item Form | Cream | | Item Type Name | E45 Dermatological Itch Relief Cream 500g | | Item Volume | 500 Millilitres | | Item Weight | 550 Grams | | Item dimensions L x W x H | 50 x 50 x 240 millimetres | | Item volume | 500 Millilitres | | Manufacturer | E45 | | Manufacturer Part Number | 285-3331 | | Material Type Free | Paraben Free | | Model Name | E45 Dermatological Itch Relief Cream, Moisturising Dual Action Treatment for Itchy and Irritated Skin, 500g | | Model Number | 348713 | | Number of Items | 1 | | Other Special Features of the Product | Travel Size | | Recommended Uses For Product | Eczema | | Scent Name | Unscented | | Skin Care Application Time | Anytime | | Skin Type | All | | Special Ingredients | Lauromacrogols 3.0%w/w, Urea 5.0%w/w | | Special feature | Travel Size | | Specific Uses For Product | Eczema | | Sun Protection | SPF 50 Sun Protection Factor (SPF) | | Target Use Body Part | Whole Body | | Unit Count | 500.0 gram | ## Product Details - **Active ingredients:** urea - **Age range (description):** Adult - **Brand:** E45 - **Item dimensions L x W x H:** 50 x 50 x 240 millimetres - **Item form:** Cream - **Item volume:** 500 Millilitres - **Number of items:** 1 - **Scent:** Unscented - **Skin type:** All - **Special feature:** Travel Size ## Images ![E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested - Image 1](https://m.media-amazon.com/images/I/51Y6C5624FL.jpg) ![E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested - Image 2](https://m.media-amazon.com/images/I/71tydZbxzDL.jpg) ![E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested - Image 3](https://m.media-amazon.com/images/I/71Oy+XLdBRL.jpg) ![E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested - Image 4](https://m.media-amazon.com/images/I/61dTh1Gc+bL.jpg) ![E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested - Image 5](https://m.media-amazon.com/images/I/71ZA9ahLkKL.jpg) ## Questions & Answers **Q: Is this antibacterial?** A: It does not state anywhere on the container that it is antibacterial. My mother has very sensitive skin and prone to itching and E45 itch relief cream helps her condition. **Q: What is the expiry date please** A: It is about three years or so. The actual expiry date is printed on the label, near the back , within a small blue printed area about one inch square. I expect it would last much longer. **Q: ordered 1 500 gr m itch reamand bill comes ?!£8; please correct it** A: THe price in UK is approximately £25 per 500ml **Q: Is this product good to use for prickly heat rash please** A: Hi there, Good question; Product should not be used on infected or inflamed skin. However we would suggest speaking to a health care professional and getting their advice to check if E45 Itch Relief Cream would be suitable for your specific needs.[ E45 Itch Relief Cream for pruritus, eczema, dermatitis, and scaling skin conditions. Always read the label.] ## Customer Reviews ### ⭐⭐⭐⭐⭐ Works well *by D***P on 14 May 2026* Really works well make sure you choose the correct product, cream not the cheaper lotion which is a good moisturiser but does nothing for itchy backs. Good dispenser ### ⭐⭐⭐⭐⭐ Does a good job *by A***R on 10 July 2026* Very cooling and comforting when applied to my itchy skin. Much more effective than itch relieving shower soap for me. ### ⭐⭐⭐⭐⭐ OMG THIS WORKED ITS A MIRACLE *by G***Y on 26 July 2025* Well I didn’t hold out much hope as nothing so far has taken away my Itching. But OMG as soon as it was applied. It felt cold which was amazing in itself. But the Itch was gone. I’m so happy. I am totally bedbound. I can’t even move by myself. So when I get an itch which I do all of the time. It’s horrible as I can’t reach it and also as my skin is so fragile. Scratching just opens it all up. I can’t sleep at night because of the itching. I can’t describe the feeling if not itching. It’s amazing. Just give it a go. What gave you got to lose. And yes it might be a tad expensive. But a little goes along way. And taking away the itching. I would have paid anything. So to me this is a small price to pay. ## Frequently Bought Together - E45 Itch Relief Cream 500G - E45 Wash Cream 250ml - E45 shower cream 200ml --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.hr/products/49917744-e45-itch-relief-cream-500g-for-eczema-dry-skin-dermatitis](https://www.desertcart.hr/products/49917744-e45-itch-relief-cream-500g-for-eczema-dry-skin-dermatitis) --- *Product available on Desertcart Croatia* *Store origin: HR* *Last updated: 2026-07-16*