---
product_id: 621943423
title: "Exosome Shot Zero 2,000 PPM Spicule Facial Serum"
brand: "medicube"
price: "€ 31.84"
currency: EUR
in_stock: true
reviews_count: 13
category: "Medicube"
url: https://www.desertcart.hr/products/621943423-exosome-shot-zero-2-000-ppm-spicule-facial-serum
store_origin: HR
region: Croatia
---

# 242% enhanced absorption AHA+BHA+PHA gentle exfoliation 15M patented Exosome shots Exosome Shot Zero 2,000 PPM Spicule Facial Serum

**Brand:** medicube
**Price:** € 31.84
**Availability:** ✅ In Stock

## Summary

> ✨ Unlock your skin’s future with every micro-shot!

## Quick Answers

- **What is this?** Exosome Shot Zero 2,000 PPM Spicule Facial Serum by medicube
- **How much does it cost?** € 31.84 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/621943423-exosome-shot-zero-2-000-ppm-spicule-facial-serum)

## Best For

- medicube enthusiasts

## Why This Product

- Trusted medicube brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Hydration Powerhouse:** Supercharges ingredient absorption by 242%, locking in moisture and leaving skin supple and radiant.
- • **Precision Micro-Delivery:** 15 million patented Exosome shots target pores with pinpoint accuracy for visible skin transformation.
- • **Clinically Proven & Gentle:** Non-comedogenic, low-irritation formula perfect for sensitive skin types craving effective results.
- • **Next-Gen Exosome-Coated Tech:** Advanced spicule design penetrates deep to boost skin vitality and energy like never before.
- • **Seamless Routine Integration:** Effortlessly fits into your skincare ritual, enhancing effects when paired with Medicube’s AGE-R Booster Pro.

## Overview

Medicube Exosome Shot Zero 2,000 PPM Spicule Facial Serum is a cutting-edge Korean skincare booster featuring 15 million patented Exosome shots and a unique micro-needle spicule design. Clinically proven to enhance absorption by 242%, it combines gentle exfoliation (AHA, BHA, PHA) with powerful hydration and skin barrier support, delivering visible improvements in texture, pore size, and radiance without irritation. Ideal for all skin types, this serum is a viral sensation for those seeking precise, next-level skin rejuvenation.

## Description

Buy medicube Exosome Shot Zero 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum with Exosome, AHA+BHA+PHA - Pore Care, Dead Skin Cells, Skin Texture, Korean Skincare, 1.01 fl.oz on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Amazing Results in Just One Week! My Skin Has Never Looked Better! - I’ve been using the Medicube Exosome Shot Zero 2,000 PPM Serum consistently, and I’m honestly blown away by how quickly it started working. I’ve tried plenty of skincare products that promise smoother texture and smaller pores, but this is one of the few that actually delivered visible results! Within about one week, I noticed a real difference in my skin. The rough patches I usually struggle with felt softer, and my overall texture looked more refined. My skin started feeling smoother to the touch, and even my makeup applied better because the surface was more even. It wasn’t a dramatic overnight change, but it was a steady, noticeable improvement that kept getting better each day. The formula is lightweight and absorbs quickly without any sticky residue. I love that it combines exosomes with AHA, BHA, and PHA, because it gently exfoliates while supporting skin renewal, all without irritation. Even with the active ingredients, I didn’t experience redness or sensitivity, which is rare for me. I definitely feel the tingling or “needles” but it wasn’t bad at all After continued use, my skin looks healthier, clearer, and more balanced. The smoothness is the biggest difference, but I also feel like my pores look tighter and my complexion has a subtle glow that wasn’t there before. Overall, this serum has earned a permanent spot in my routine. If you’re dealing with uneven texture, dullness, or just want smoother, more refined skin, this product is absolutely worth trying. It’s one of the few skincare items where I can confidently say: I saw real results.
Review: I was nervous to try, but it's so mild! - I was nervous to try this because of the spicules, since I’ve never used a spicule based product before. I chose the 2000 PPM Exosome Shot to start on the gentler side, and I was pleasantly surprised by how mild it actually feels on the skin. I use this once a week after cleansing (about two pumps), gently pat it in, and then follow with my nighttime moisturizer. There is a very slight pokey sensation on application, but it’s not painful or irritating- just noticeable enough to know it’s there. By morning, my skin looks noticeably smoother, more refined, and almost glass-like. I have reactive, eczema-prone skin, so I’m usually very cautious with exfoliating products and anything containing acids. Despite the AHA + BHA + PHA blend and spicules, I have not experienced dryness, itching, or sensitivity with weekly use. The exfoliation feels effective, but not harsh or barrier stripping. I also like that the formula includes niacinamide and soothing components alongside the exfoliants, which likely help balance the overall results. The texture is lightweight, spreads easily, and layers well with other skincare without pilling or being sticky. Overall, this is a great entry level spicule serum if you’re curious but hesitant. It delivers smoother, more refined looking skin texture without the aggressive irritation I anticipated. I will likely continue with the 2000 PPM for maintenance, and may consider trying the higher strength once my skin fully acclimates.

## Features

- Viral product beloved by everyone - Transform your skin with the Exosome + Shot Booster. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots for precise treatment, this booster delivers active ingredients directly to your pores to tackle various skin issues.
- Exosome-Coated Technology - Harness the next-generation skincare with Exosome-coated Spicule and Exosome, penetrating deep into the skin to deliver active ingredients effectively. Our advanced formula is designed to address a range of skin concerns, from pore care to enhancing skin vitality and energy.
- Superior Absorption & Hydration - Achieve unmatched hydration and absorption rates with our formula, which enhances active ingredient uptake by 242% compared to standalone use. Ingredients like Niacinamide and Panthenol boost skin barrier and improve hydration levels, ensuring your skin remains supple and radiant.
- Clinically Proven & Gentle on Skin - Enjoy peace of mind with our clinically validated Tingling Ampoule that is non-comedogenic, tested to be low-irritating, gluten-free, and free from artificial colors. Suitable for all skin types, including sensitive skin.
- Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule easily with a three-step routine, starting with a cleansing pad, followed by the Zero One Day Exosome Shot, and finish with a water-based moisturizer like Medicube’s Collagen Jelly Cream. For an added boost, use after the "Air Shot Mode" of the AGE-R Booster Pro to maximize effects.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0D16L5F2M |
| Best Sellers Rank | #359 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #18 in Facial Serums |
| Brand | medicube |
| Brand Name | medicube |
| Customer Reviews | 4.5 out of 5 stars 3,828 Reviews |
| Item Form | Ampoule |
| Item Highlight | Liquid Skin Booster Serum with Exosome, AHA+BHA+PHA - Pore Care, Dead Skin Cells, Skin Texture, Korean Skincare, 1.01 fl.oz |
| Item Volume | 0.4 kg |
| Item Weight | 30 milligrams |
| Manufacturer | Medicube |
| Manufacturer Part Number | PMEKR14036 |
| Model Number | 8809981334928 |
| Number of Items | 1 |
| Product Benefits | Blemishes Treatment |
| Recommended Uses For Product | Dead Skin Cells,Skin Texture |
| Scent | Aloe |
| Scent Name | Aloe |
| Skin Tone | All |
| Skin Type | All, Combination, Dry, Oily, Oily Acne Prone, Sensitive |
| Special Ingredients | Alpha Hydroxy, Collagen, Minerals |
| Target Use Body Part | Face |
| Unit Count | 1.01 Fluid Ounces |
| Use for | Face |

## Product Details

- **Product Benefits:** Blemishes Treatment
- **Scent:** Aloe
- **Skin Type:** All, Combination, Dry, Oily, Oily Acne Prone, Sensitive
- **Special Ingredients:** Alpha Hydroxy, Collagen, Minerals
- **Use for:** Face

## Images

![Exosome Shot Zero 2,000 PPM Spicule Facial Serum - Image 1](https://m.media-amazon.com/images/I/71bfHCGMlEL.jpg)

## Available Options

This product comes in different **Pattern, Size** options.

## Questions & Answers

**Q: What are exosomes?**
A: Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information

**Q: What is the source and function of the Lacto Exosome in Zero Exosome Shot?**
A: The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps b

**Q: Is it normal for my face to tingle after application?**
A: It contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. Please adjust usage based on skin sensitivity.

**Q: Do I simply wash it off or do I maintain my regular skincare routine afterwards?**
A: This product is not meant to be rinsed off. Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.

**Q: Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?**
A: The spicules are designed to naturally shed along with the dead skin over several days after application. Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Amazing Results in Just One Week! My Skin Has Never Looked Better!
*by J***E on July 12, 2026*

I’ve been using the Medicube Exosome Shot Zero 2,000 PPM Serum consistently, and I’m honestly blown away by how quickly it started working. I’ve tried plenty of skincare products that promise smoother texture and smaller pores, but this is one of the few that actually delivered visible results! Within about one week, I noticed a real difference in my skin. The rough patches I usually struggle with felt softer, and my overall texture looked more refined. My skin started feeling smoother to the touch, and even my makeup applied better because the surface was more even. It wasn’t a dramatic overnight change, but it was a steady, noticeable improvement that kept getting better each day. The formula is lightweight and absorbs quickly without any sticky residue. I love that it combines exosomes with AHA, BHA, and PHA, because it gently exfoliates while supporting skin renewal, all without irritation. Even with the active ingredients, I didn’t experience redness or sensitivity, which is rare for me. I definitely feel the tingling or “needles” but it wasn’t bad at all After continued use, my skin looks healthier, clearer, and more balanced. The smoothness is the biggest difference, but I also feel like my pores look tighter and my complexion has a subtle glow that wasn’t there before. Overall, this serum has earned a permanent spot in my routine. If you’re dealing with uneven texture, dullness, or just want smoother, more refined skin, this product is absolutely worth trying. It’s one of the few skincare items where I can confidently say: I saw real results.

### ⭐⭐⭐⭐⭐ I was nervous to try, but it's so mild!
*by M***E on February 25, 2026*

I was nervous to try this because of the spicules, since I’ve never used a spicule based product before. I chose the 2000 PPM Exosome Shot to start on the gentler side, and I was pleasantly surprised by how mild it actually feels on the skin. I use this once a week after cleansing (about two pumps), gently pat it in, and then follow with my nighttime moisturizer. There is a very slight pokey sensation on application, but it’s not painful or irritating- just noticeable enough to know it’s there. By morning, my skin looks noticeably smoother, more refined, and almost glass-like. I have reactive, eczema-prone skin, so I’m usually very cautious with exfoliating products and anything containing acids. Despite the AHA + BHA + PHA blend and spicules, I have not experienced dryness, itching, or sensitivity with weekly use. The exfoliation feels effective, but not harsh or barrier stripping. I also like that the formula includes niacinamide and soothing components alongside the exfoliants, which likely help balance the overall results. The texture is lightweight, spreads easily, and layers well with other skincare without pilling or being sticky. Overall, this is a great entry level spicule serum if you’re curious but hesitant. It delivers smoother, more refined looking skin texture without the aggressive irritation I anticipated. I will likely continue with the 2000 PPM for maintenance, and may consider trying the higher strength once my skin fully acclimates.

### ⭐⭐⭐⭐⭐ Yes this product does work very well with an already established skincare routine.
*by A***E on December 2, 2025*

Ima be honest, I was skeptical on how well this product works after hearing it all over tiki tok but they are definitely onto something. I got the exosome 2000 yesterday and used it the same night. I admit, yes it does itch and sting but its tolerable and went away after like 30 - 45 mins of using. It didnt make my skin red, which was surprising. My current routine is: Pm only; - anua oil cleanser - anua deep pore cleanser - anua 70 toner - (now) medicue one day exosome shot 2000 - (now) corsx vitamin c 23 - corsx snail mucin essence - Neutrogena firm moisturizer or anua daily lotion [ i like to switch between the two ] Im 31 years old, my skin is textured with dark spots, dull and I have a chubby face with few fine lines, scars and huge pores on the apples of my cheeks and some on my nose. I get millia under my eyes/ on the top of my cheek sometimes. Its not too close to the thin skin under my eyes. Today ( the next morning) I noticed my pore are visibly smaller. Wow really?! Yes really! even after 1 use. It's like an exfoliant that my skin needed. (Paula's choice bha, aha exfoliating toner sucks and did not work for me). I noticed my skin was softer and the Milia looks like it opened up and the ball inside is ready to fall out. This product will become part of my skincare routine for sure! I will repurchase and highly suggest this product.

## Frequently Bought Together

- medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz
- Medicube Zero Pore Pads 2.0, Dual-Textured Facial Toner Pads for Exfoliation and Pore Care with 4.5% AHA Lactic Acid & 0.45% BHA Salicylic Acid, Ideal for All Skin Types, Korean Skin Care (70 Pads)
- medicube Collagen Jelly Cream- Niacinamide & Freeze-Dried Hydrolyzed Collagen - Boosts skin's barrier hydration and gives 24h Glow & Lifted Look - Korean skincare (1.69 Fl Oz (Pack of 1))

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*Product available on Desertcart Croatia*
*Store origin: HR*
*Last updated: 2026-09-22*