---
product_id: 6888483
title: "Nature's Way 5-HTP, L-5-Hydroxytryptophan, Helps Make Serotonin to Promote a Positive Outlook*, Vitamin B6, Vitamin C, Griffonia Bean Extract, 60 Tablets (Packaging May Vary)"
brand: "nature's way"
price: "€ 18.13"
currency: EUR
in_stock: true
reviews_count: 4
category: "Nature's Way"
url: https://www.desertcart.hr/products/6888483-natures-way-5-htp-l-5-hydroxytryptophan-helps-make-serotonin
store_origin: HR
region: Croatia
---

# Vegan & gluten-free formula 100mg 5-HTP per 2 tablets Enteric coated for brain delivery Nature's Way 5-HTP, L-5-Hydroxytryptophan, Helps Make Serotonin to Promote a Positive Outlook*, Vitamin B6, Vitamin C, Griffonia Bean Extract, 60 Tablets (Packaging May Vary)

**Brand:** nature's way
**Price:** € 18.13
**Availability:** ✅ In Stock

## Summary

> 🌙 Elevate your mood & sleep smarter with Nature’s Way 5-HTP — your brain’s natural glow-up!

## Quick Answers

- **What is this?** Nature's Way 5-HTP, L-5-Hydroxytryptophan, Helps Make Serotonin to Promote a Positive Outlook*, Vitamin B6, Vitamin C, Griffonia Bean Extract, 60 Tablets (Packaging May Vary) by nature's way
- **How much does it cost?** € 18.13 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/6888483-natures-way-5-htp-l-5-hydroxytryptophan-helps-make-serotonin)

## Best For

- nature's way enthusiasts

## Why This Product

- Trusted nature's way brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Vitamin Synergy:** Includes Vitamins B6 & C to optimize conversion of 5-HTP into serotonin—your natural mood enhancer.
- • **Clean & Conscious:** Gluten-free, vegan, and free from artificial colors, soy, dairy, and gelatin—pure wellness you can trust.
- • **Precision Delivery:** Enteric coating ensures 5-HTP survives stomach acid to efficiently cross the blood-brain barrier.
- • **Boost Your Brain Fuel:** 100mg 5-HTP from Griffonia bean extract powers serotonin synthesis for mood uplift.
- • **Sleep & Serenity Support:** Clinically favored by users for promoting restful sleep, calmness, and curbing sugar cravings.

## Overview

Nature's Way 5-HTP delivers 100mg of pure 5-Hydroxytryptophan per serving, extracted from Griffonia simplicifolia beans, combined with essential Vitamins B6 and C. This vegan, gluten-free, enteric-coated formula is designed to promote serotonin production, supporting a positive mood, better sleep quality, and overall mental wellness. Trusted for over 50 years, it’s a clean, effective supplement tailored for mindful adults seeking natural brain and mood support.

## Description

Nature's Way 5-HTP helps make serotonin to promote a positive outlook.* With vitamins B6 and C. 100 mg 5-HTP from griffonia seed extract per 2-tablet serving. *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Review: Must for sleep - I take 2 tablets (100 mg) nightly. It's a must for sleep. It's important to take it on an empty stomach or its expensive urine. Unless it's taken with something that only has carbs but not any protein. Tryptophan is an amino acid which competes with all other amino acids for metabolism. So I take mine with a small serving of a simple carb. (simple carbs are faster acting than complex carbs like in bread or potatoes). I take it with a small glass of apple juice or other fruit juice on an empty stomach. This helps the efficiency of the metabolism. When taken on an empty stomach with a small simple carb serving without protein, is like a guided missile from your stomach to your brain. It gives it the best chance at crossing the BBB- blood brain barrier. Tryptophan is the precursor for serotonin. Serotonin is the precursor for melatonin. Melatonin is the hormone that is secreted by the pineal gland and is known to regulate the sleep cycle by controlling the circadian rhythm. Tryptophan is broken down in your body to 5HTP so this supplement has already taken that step for you. 5HTP must be enteric coated or it won't survive your stomach acid for brain metabolism. Also, it is known that Vitamin C and Vitamin B6 are necessary for conversion of 5HTP to serotonin. This supplement is both enteric coated and has Vit C & B6 already in it. It is the only one that I know of that has both key aspects and I've been taking 5HTP for sleep for over a decade. For my nighttime sleeping regimen, I take two pills of this 5HTP (100 mg) with apple juice on an empty stomach & wait about an hour and then take 5-10 mg of controlled released melatonin. It only makes sense with our pharmacology and how neurotransmitters work in our brains. Tryptophan is converted to 5HTP which is then converted to serotonin (some of which is able to cross the blood brain barrier-5HTP is more efficient at this than tryptophan alone). Finally and most importantly, serotonin is the precursor to melatonin. You must have a sufficient amount of serotonin on board for melatonin to become converted in your brain. 5HTP is like gas for your brain. Then, if you don't already have serotonin (to be able to convert to melatonin), it's like trying to drive a car with gas but no oil. It's so important to understand how to take 5HTP properly and to use the correct supplement. Sometimes, I will have some good deep sleep with REM (dreams) and will wake up at 2-3 am and unable to get back asleep. So I will take 50 mg more of 5HTP & a 5 mg instant release supplement of melatonin. The conversion is tryptophan->5HTP->serotonin-> melatonin. Its different for everyone but I find that I have to take it on a regular basis for about 2 weeks nightly to start receiving the benefits. I have better sleep with more dreams and REM sleep. I know personally from my dream recall and my Fitbit is usually pretty accurate too. Some people are able to take it sporadically as needed and it works. The correct dosage and timing is different for everybody. You just have to experiment a bit and start out low and work your way up to the dosage that feels right for your best sleep. For the timing for sleep, I eat dinner early purposely for my best nights sleep, around 5:30. You don't sleep as well when your body is also working on digesting your food (late night snacks) at the same time. I give my body three hours to digest my food so I'm taking it on an empty stomach. I take my 5HTP around 9 pm, melatonin around 10 pm and am usually asleep by 11 pm. By nature, I have trouble getting to sleep and falling to sleep but this helps a lot. For some of the people that rated it one star because it had no effect, it could be that they didn't take it properly; on an empty stomach or long enough. I wish the instructions would say to take on an empty stomach instead of with a meal. Some experts believe that if it is enteric coated, that it can be taken with food and it will be just as effective. All I can say is personally, it only works for me on an empty stomach. Our neurotransmitters in out brains are derived from amino acids from protein. The amino acids are all in competition with one another for their designated neurotransmitter. It's like a lock and key. Tryptophan isn't found in large quantities in most foods compared to other essential amino acids so it losses out in competition. When taken on an empty stomach there is no competition. Add a small amount of some fruit juice (simple carb) and it will help the metabolism and efficiency.
Review: Great Supplement, if Needed - I found this product to work very well for me. It assisted my ascent from depression, curbs my craving for complex sugars, helps me to feel calm & serene. Even assists with sleep! Can't say enough about it. I think it only works if you're deficient in serotonin, though...Which I turned out to be, as I responded well to it. My particular dosage, after I worked up to it (it can make you nauseous in the beginning if you take too much @ once..) Is Two 50mg. tablets, every 4 hours. So, I program my phone to beep at: 10a, 2p, 6p, & 10p. If I'm PMS-ing & craving sweets more than normally, I'll take one or two & that makes them subside. This is Obviously just my own personal schedule I worked out; Perhaps you'll find another works better for you. Good Luck~ & Good Health!! : D

## Features

- Nature's Way 5-HTP helps make serotonin to promote a positive outlook.*
- Formulated with vitamins B6 and C.
- Adults take 1-2 tablets three times daily with meals.
- Gluten-free and vegan. No wheat, soy, dairy, gelatin, or artificial colors.
- At Nature’s Way, we believe nature is the ultimate problem solver. For over 50 years, we have looked to the natural world for inspiration. Our quality vitamins and supplements are formulated to help you find your way to wellness.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0009ET9S6 |
| ASIN  | B0009ET9S6 |
| Age Range Description | Adult |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #83,364 in Health & Household ( See Top 100 in Health & Household ) #86 in 5-HTP Nutritional Supplements |
| Brand Name | Nature's Way |
| Container Type | Bottle |
| Customer Reviews | 4.5 4.5 out of 5 stars (527) |
| Date First Available  | September 16, 2003 |
| Diet Type | Vegan, Vegetarian |
| Dosage Form | Tablet |
| Flavor | Unflavored |
| Global Trade Identification Number | 00033674452509 |
| Is Discontinued By Manufacturer  | No |
| Item Dimensions | 2.02 x 2.02 x 4.05 inches |
| Item Form | Tablet |
| Item Nype Name | DIETARY_SUPPLEMENTS |
| Item Weight | 0.11 Pounds |
| Item model number  | 45250 |
| Manufacturer | Nature's Way |
| Manufacturer  | Nature's Way |
| Manufacturer Part Number | 45250 |
| Material Features | Gluten Free |
| Model Name | 5-HTP |
| Model Number | 45250 |
| Number of Items | 1 |
| Primary Supplement Type | 5-HTP |
| Product Benefits | Nutritional Support |
| Product Dimensions  | 2.02 x 2.02 x 4.05 inches; 1.76 ounces |
| Special Ingredients | 5-Hydroxytryptophan |
| Specific Uses For Product | 5-Hydroxytryptophan (5-HTP) is the precursor to serotonin, a mood and appetite regulating neurotransmitter produced within the body.* It has been combined with Vitamin B6, an important cofactor in the conversion to serotonin.*Nature's Way® uses 5-HTP extracted from Griffonia simplicifolia beans. |
| Total Servings Per Container | 60 |
| UPC | 033674452509 |
| Unit Count | 60 Count |

## Product Details

- **Brand:** Nature's Way
- **Diet Type:** Vegan, Vegetarian
- **Flavor:** Unflavored
- **Item Form:** Tablet
- **Item Weight:** 0.11 Pounds
- **Item dimensions L x W x H:** 2.02 x 2.02 x 4.05 inches
- **Primary Supplement Type:** 5-HTP
- **Product Benefits:** Nutritional Support
- **Special Ingredients:** 5-Hydroxytryptophan
- **Unit Count:** 60 Count

## Images

![Nature's Way 5-HTP, L-5-Hydroxytryptophan, Helps Make Serotonin to Promote a Positive Outlook*, Vitamin B6, Vitamin C, Griffonia Bean Extract, 60 Tablets (Packaging May Vary) - Image 1](https://m.media-amazon.com/images/I/71gESbjip-L.jpg)

## Questions & Answers

**Q: The front of the bottle says 50mg but the back says 100mg.  Which is it, please?**
A: They are 50 mg each. The back of this bottle says the serving size is 2 tablets which is why it says 100 mg. If you read the recommendations on the bottle it even says, "Start with a low dose of one tablet (50 mg) taken daily with a meal."

**Q: is this time-release?  i plan to cut them in half as 50mg is too much for me.**
A: No I do not believe they are time released.

**Q: Is this enteric coated ?**
A: This supplement is enteric coated.Mood support* Enteric-coated tablets* Helps regulate sleep patterns

**Q: What is trytophane**
A: It's an amino acid. https://www.esupplements.com/best-l-tryptophan-supplements/?utm_source=bing&utm_medium=cpc&utm_campaign=10%20Best%20Lists&utm_term=tryptophan&utm_content=tryptophan

## Customer Reviews

### ⭐⭐⭐⭐⭐ Must for sleep
*by I***1 on September 21, 2023*

I take 2 tablets (100 mg) nightly. It's a must for sleep. It's important to take it on an empty stomach or its expensive urine. Unless it's taken with something that only has carbs but not any protein. Tryptophan is an amino acid which competes with all other amino acids for metabolism. So I take mine with a small serving of a simple carb. (simple carbs are faster acting than complex carbs like in bread or potatoes). I take it with a small glass of apple juice or other fruit juice on an empty stomach. This helps the efficiency of the metabolism. When taken on an empty stomach with a small simple carb serving without protein, is like a guided missile from your stomach to your brain. It gives it the best chance at crossing the BBB- blood brain barrier. Tryptophan is the precursor for serotonin. Serotonin is the precursor for melatonin. Melatonin is the hormone that is secreted by the pineal gland and is known to regulate the sleep cycle by controlling the circadian rhythm. Tryptophan is broken down in your body to 5HTP so this supplement has already taken that step for you. 5HTP must be enteric coated or it won't survive your stomach acid for brain metabolism. Also, it is known that Vitamin C and Vitamin B6 are necessary for conversion of 5HTP to serotonin. This supplement is both enteric coated and has Vit C & B6 already in it. It is the only one that I know of that has both key aspects and I've been taking 5HTP for sleep for over a decade. For my nighttime sleeping regimen, I take two pills of this 5HTP (100 mg) with apple juice on an empty stomach & wait about an hour and then take 5-10 mg of controlled released melatonin. It only makes sense with our pharmacology and how neurotransmitters work in our brains. Tryptophan is converted to 5HTP which is then converted to serotonin (some of which is able to cross the blood brain barrier-5HTP is more efficient at this than tryptophan alone). Finally and most importantly, serotonin is the precursor to melatonin. You must have a sufficient amount of serotonin on board for melatonin to become converted in your brain. 5HTP is like gas for your brain. Then, if you don't already have serotonin (to be able to convert to melatonin), it's like trying to drive a car with gas but no oil. It's so important to understand how to take 5HTP properly and to use the correct supplement. Sometimes, I will have some good deep sleep with REM (dreams) and will wake up at 2-3 am and unable to get back asleep. So I will take 50 mg more of 5HTP & a 5 mg instant release supplement of melatonin. The conversion is tryptophan->5HTP->serotonin-> melatonin. Its different for everyone but I find that I have to take it on a regular basis for about 2 weeks nightly to start receiving the benefits. I have better sleep with more dreams and REM sleep. I know personally from my dream recall and my Fitbit is usually pretty accurate too. Some people are able to take it sporadically as needed and it works. The correct dosage and timing is different for everybody. You just have to experiment a bit and start out low and work your way up to the dosage that feels right for your best sleep. For the timing for sleep, I eat dinner early purposely for my best nights sleep, around 5:30. You don't sleep as well when your body is also working on digesting your food (late night snacks) at the same time. I give my body three hours to digest my food so I'm taking it on an empty stomach. I take my 5HTP around 9 pm, melatonin around 10 pm and am usually asleep by 11 pm. By nature, I have trouble getting to sleep and falling to sleep but this helps a lot. For some of the people that rated it one star because it had no effect, it could be that they didn't take it properly; on an empty stomach or long enough. I wish the instructions would say to take on an empty stomach instead of with a meal. Some experts believe that if it is enteric coated, that it can be taken with food and it will be just as effective. All I can say is personally, it only works for me on an empty stomach. Our neurotransmitters in out brains are derived from amino acids from protein. The amino acids are all in competition with one another for their designated neurotransmitter. It's like a lock and key. Tryptophan isn't found in large quantities in most foods compared to other essential amino acids so it losses out in competition. When taken on an empty stomach there is no competition. Add a small amount of some fruit juice (simple carb) and it will help the metabolism and efficiency.

### ⭐⭐⭐⭐⭐ Great Supplement, if Needed
*by H***L on September 6, 2006*

I found this product to work very well for me. It assisted my ascent from depression, curbs my craving for complex sugars, helps me to feel calm & serene. Even assists with sleep! Can't say enough about it. I think it only works if you're deficient in serotonin, though...Which I turned out to be, as I responded well to it. My particular dosage, after I worked up to it (it can make you nauseous in the beginning if you take too much @ once..) Is Two 50mg. tablets, every 4 hours. So, I program my phone to beep at: 10a, 2p, 6p, & 10p. If I'm PMS-ing & craving sweets more than normally, I'll take one or two & that makes them subside. This is Obviously just my own personal schedule I worked out; Perhaps you'll find another works better for you. Good Luck~ & Good Health!! : D

### ⭐⭐⭐⭐⭐ Insomnia & Chronic Pain
*by L***8 on September 15, 2011*

As someone who has had a serious pain condition since I was 8 years old which also causes a metabolism imbalance making insomnia something I have faced every night of my life, I have been pleasantly surprised by 5-HTP. I'm sleeping. I did studies on the supplement before purchasing to assure it didn't have adverse side effects to the many narcotics I live on. I had no conflicts w/ any meds I'm on so I gave it a go. I read that it can cause vivid dreaming and nightmares, anxiety and upset stomach but for me it has been wonderful. I have always been a vivid dreamer as well as lucid dreamer when I have been able to sleep, so for me, I dream more than normal but I haven't experienced any nightmares... though I am dreaming of people that I haven't thought about in 20+ years, so it must be where and how it acts on the brain. I haven't had the horrific nightmares so many people warned about but honestly, what are nightmares for some aren't nightmares for all. One thing I have realized that could be a concern for some people similar to me that have suffered from insomnia for 30+ years is I have become almost addicted to sleep and so fascinated by the dreams that I have become a dreamchaser. This is polar opposite to anything I've experienced in trying to sleep my whole life and I enjoy it so much all I want to do is sleep. My schedule and life allows for it, so I just go with it. I'm more well rested than I've ever been. As for pain, I am now able to take a little less breakthrough pain medication than before. I don't find it a relaxant, and I take it primarily for sleep, but I don't have to take as much extra pain medication at night as I had previously. On a side note, I have lost a minor amount of weight. This is welcome. I also take Nutra Sleep, 5-HTP, and several other sleep supplements (L-Trypt, Melatonin, SomaSleep) but I can highly recommend 5-HTP without hesitation, especially for people suffering from RSD/CRPS, FMS, CFS, who are not taking drugs that could cause adverse reaction. Be sure to research all meds you are on or talk to your pharmacist or doctor to confirm you are not taking something that could cause problems. Sleep is good but Safety is better.

## Frequently Bought Together

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*Product available on Desertcart Croatia*
*Store origin: HR*
*Last updated: 2026-05-22*