---
product_id: 81953289
title: "- Advanced GI Care - High Potency Probiotic - 450 Billion CFU Live Probiotics, Original De Simone Formulation, 60 Packets of Unflavored Powder."
brand: "visbiome"
price: "€ 484.31"
currency: EUR
in_stock: true
reviews_count: 8
category: "Visbiome"
url: https://www.desertcart.hr/products/81953289-advanced-gi-care-high-potency-probiotic-450-billion-cfu-live
store_origin: HR
region: Croatia
---

# 450B CFU ultra-potent probiotic 100% recyclable sustainable packaging Cold-chain shipped for max freshness - Advanced GI Care - High Potency Probiotic - 450 Billion CFU Live Probiotics, Original De Simone Formulation, 60 Packets of Unflavored Powder.

**Brand:** visbiome
**Price:** € 484.31
**Availability:** ✅ In Stock

## Summary

> 🦠 Elevate your gut game with the probiotic pros’ secret weapon!

## Quick Answers

- **What is this?** - Advanced GI Care - High Potency Probiotic - 450 Billion CFU Live Probiotics, Original De Simone Formulation, 60 Packets of Unflavored Powder. by visbiome
- **How much does it cost?** € 484.31 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.hr](https://www.desertcart.hr/products/81953289-advanced-gi-care-high-potency-probiotic-450-billion-cfu-live)

## Best For

- visbiome enthusiasts

## Why This Product

- Trusted visbiome brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Flexible Daily Use:** Unflavored powder easily mixes into any drink or meal—ditch pills without sacrificing potency.
- • **Gut Health Powerhouse:** 450 billion CFU with 8 clinically-tested strains for unmatched digestive support.
- • **Sustainably Delivered:** Arrives cold-packed with temperature monitoring in eco-friendly recyclable materials.
- • **Pure & Clean Ingredients:** Low-FODMAP, Non-GMO, gluten-free, and free from cornstarch for clean-label confidence.
- • **Clinically Proven Formula:** Backed by 100+ human clinical trials as a trusted medical food.

## Overview

Visbiome® Advanced GI Care delivers a potent 450 billion CFU of live probiotics per packet, featuring 8 clinically-tested strains in the original De Simone formulation. Designed for optimal gut health, it’s backed by over 100 clinical trials and shipped cold in fully recyclable packaging to ensure maximum potency. This unflavored powder offers a clean-label, low-FODMAP, and non-GMO solution that seamlessly integrates into your daily routine for superior digestive wellness.

## Description

Buy Visbiome® Advanced GI Care - High Potency Probiotic - 450 Billion CFU Live Probiotics, Original De Simone Formulation, 60 Packets of Unflavored Powder. on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Potent stuff for a candida cleanse - You need something like this if you are going to do a candida cleanse right. You want this good bacteria, and a lot of it, to take the place of the yeast you are removing from your digestive system. I've tried a candida cleanse a couple times now and I think I've finally got a good system down. Unfortunately (depending on how bad your overgrowth is) is won't be very successful with out a sugar free, low/no carb diet. I tried a cleanse without dieting and just felt terrible for the entire month. You are just killing yeast every day that is regrowing from the sugar you feed it. A low carb diet works even better but if you can remove nearly all carbs it just makes the cleanse so much easier. Just eat meat and veggies during your cleanse and you're good. Milk Thistle supplements help you deal with any die off symptoms and make it easier on your liver. I divide my cleanse supplements after breakfast and lunch. They include coconut oil/caprylic acid, oregano oil, garlic pills, grapefruit seed extract, among others. Start with one natural anti-fungal and slowly add others over days so at one point you are hitting the yeast with at least 3 different types so it can't adapt. Then, maybe an hour before dinner, take the Visibiome. The yeast that has been killed throughout the day will hopefully be replaced with the good bacteria in the probiotics. And then your body can rest and absorb the probiotics while you sleep until you're ready to do it again the next day. Do this for at least a month. Take breaks or cut back on anti-fungal supplements if you are feeling really terrible. If your overgrowth is really bad you may need to do multiple cleanses over months. I've been doing one for nearly the entire year of 2020 and I'm finally starting to feel better than I have in a decade. (I was given Xifaxin 2 years ago which nuked my gut and made everything a lot worse) If you are getting bad reactions it's because the cleanse is working... don't give up. Just cut back and keep at it. You'll get there. Good luck.
Review: Great product - Great product for my dog, who is paralyzed and prone to UTIs but otherwise very active. It helps keep her healthy in every respect other than her chronic condition. Really impressed by the care in packaging so this arrived at the refrigerated temperature it requires to be potent.

## Features

- POWERFUL PROBIOTIC BLEND: Contains 8 clinically-tested strains with a potent 450 billion CFU per packet. Designed for optimal gut health in both men and women.
- PROVEN EFFICACY: Boasts over 100 human clinical trials as a recognized medical food.
- SUSTAINABLY PACKAGED: Ships cold in a 100% curbside recyclable insulated cooler, equipped with ice packs and a temperature monitoring device, ensuring maximum potency upon arrival.
- PURE & SAFE INGREDIENTS: Low-FODMAP Certified, Clean Label Certified, Non-GMO, Cornstarch Free, Gluten-Free. Non-active Ingredients: corn starch. Note: Contains trace amounts of milk.
- VERSATILE POWDER FORM: Visbiome is available as an unflavored powder, offering a flexible alternative for those who prefer not to swallow pills. Easily mixable with food or beverages without altering taste, perfect for incorporating into your daily health routine.
- COLD STORAGE REQUIRED: Visbiome probiotics are shipped and stored under refrigerated conditions (36-46°F, 2-8°C) to ensure maximum potency, with the flexibility to remain effective at room temperature for up to one week.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B078SJN5YZ |
| Best Sellers Rank | #47,322 in Health & Household ( See Top 100 in Health & Household ) #227 in Acidophilus Nutritional Supplements |
| Customer Reviews | 4.6 4.6 out of 5 stars (731) |
| Date First Available  | January 3, 2018 |
| Is Discontinued By Manufacturer  | No |
| Manufacturer  | Exegi Pharma |
| Package Dimensions  | 11.4 x 11.2 x 9.4 inches; 4.58 Pounds |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** Visbiome
- **Flavor:** Unflavored
- **Item Form:** Powder
- **Item Weight:** 2.08 Kilograms
- **Number of Items:** 2
- **Package Information:** packet
- **Primary Supplement Type:** Probiotic
- **Servings per Container:** 30
- **Unit Count:** 5.4 Ounce

## Images

![- Advanced GI Care - High Potency Probiotic - 450 Billion CFU Live Probiotics, Original De Simone Formulation, 60 Packets of Unflavored Powder. - Image 1](https://m.media-amazon.com/images/I/61lqGXIEJGL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: how does it compare with VSOL#3?**
A: Visbiome contains the original De Simone Formulation used in VSL#3 before January of 2016. After this date the VSL#3 formation was changed and became dairy free. Production was of VSL#3 was moved to Italy. Inventor of the formulation previously used in VSL#3 took away the formulation from the former Sigma Tau and collaborated with ExeGi Pharma. Visbiome is made be ExeGi Pharma  the way the inventor created it over 20 years ago. Visbiome is made in the USA, the same way they made VSL#3 prior the formula change. All 60 human clinical studies for over the years was done for the formulation used in Visbiome.

**Q: How many packets are in a box?**
A: Good Day - 
There are enough packets for 30 days - 30 packets. 
I hope this helps
Regards,
Suzette

**Q: Why is the sachet twice as expensive as the pill form?**
A: Hi, 
One  sachet/packet contains 450 billion bacteria. The pill/capsule contains 112.5 billion bacteria. You would need to take 4 pills = to one packet.
Thank you.
In good health

**Q: Does the product come packaged in ice as other companies do?**
A: If shipped from an authorized seller, the product is shipped with an insulated shipper, appropriate ice packs, and a temperature monitor.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Potent stuff for a candida cleanse
*by B***B on October 25, 2020*

You need something like this if you are going to do a candida cleanse right. You want this good bacteria, and a lot of it, to take the place of the yeast you are removing from your digestive system. I've tried a candida cleanse a couple times now and I think I've finally got a good system down. Unfortunately (depending on how bad your overgrowth is) is won't be very successful with out a sugar free, low/no carb diet. I tried a cleanse without dieting and just felt terrible for the entire month. You are just killing yeast every day that is regrowing from the sugar you feed it. A low carb diet works even better but if you can remove nearly all carbs it just makes the cleanse so much easier. Just eat meat and veggies during your cleanse and you're good. Milk Thistle supplements help you deal with any die off symptoms and make it easier on your liver. I divide my cleanse supplements after breakfast and lunch. They include coconut oil/caprylic acid, oregano oil, garlic pills, grapefruit seed extract, among others. Start with one natural anti-fungal and slowly add others over days so at one point you are hitting the yeast with at least 3 different types so it can't adapt. Then, maybe an hour before dinner, take the Visibiome. The yeast that has been killed throughout the day will hopefully be replaced with the good bacteria in the probiotics. And then your body can rest and absorb the probiotics while you sleep until you're ready to do it again the next day. Do this for at least a month. Take breaks or cut back on anti-fungal supplements if you are feeling really terrible. If your overgrowth is really bad you may need to do multiple cleanses over months. I've been doing one for nearly the entire year of 2020 and I'm finally starting to feel better than I have in a decade. (I was given Xifaxin 2 years ago which nuked my gut and made everything a lot worse) If you are getting bad reactions it's because the cleanse is working... don't give up. Just cut back and keep at it. You'll get there. Good luck.

### ⭐⭐⭐⭐⭐ Great product
*by A***R on December 14, 2025*

Great product for my dog, who is paralyzed and prone to UTIs but otherwise very active. It helps keep her healthy in every respect other than her chronic condition. Really impressed by the care in packaging so this arrived at the refrigerated temperature it requires to be potent.

### ⭐⭐⭐⭐⭐ Lots of probitics
*by L***D on January 31, 2026*

Good

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*Product available on Desertcart Croatia*
*Store origin: HR*
*Last updated: 2026-02-10*