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💡 Elevate your focus and energy with the folate formula that actually works!
Opti-Folate L-Methylfolate by Carlyle delivers a potent 7.5mg dose of bioavailable folate in a gluten-free capsule form. Designed for adults with folate deficiencies or malabsorption issues, this supplement supports mental clarity and overall wellness. With 60 capsules per bottle and a 4.7-star rating from over 2,200 users, it’s a trusted choice for professionals seeking a clean, effective folate boost.





| ASIN | B07M96KFP9 |
| Age Range Description | Adult |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #42,981 in Health ( See Top 100 in Health ) #407 in Vitamin B Supplements |
| Brand | Carlyle |
| Brand Name | Carlyle |
| Customer Reviews | 4.6 out of 5 stars 2,256 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Flavour | Unflavored |
| Item Dimensions | 50 x 50 x 95 millimeters |
| Item Form | Capsule |
| Item Weight | 1.75 Ounces |
| Item form | Capsule |
| Item weight | 1.75 Ounces |
| Manufacturer | Carlyle |
| Manufacturer Part Number | CL14531 |
| Material Type Free | en_AE |
| Model Name | Carlyle |
| Model Number | CL14531 |
| Number of Items | 60 |
| Primary Supplement Type | Folic Acid,B Complex,B-complex |
| Primary supplement type | Folic Acid,B Complex,B-complex |
| Product Benefits | Nutritional Supplement |
| Specific Uses For Product | Laboratory |
| UPC | 843604101564 |
| Unit Count | 60.0 Count |
| Unit count | 60.0 Count |
S**M
High potency for a low-functioning morning
Let’s be real: nobody buys 7.5 mg of methylfolate for fun. You buy it because your doctor told you your folate levels are in the basement. This Opti-Folate formula is clean, easy to swallow, and actually bioavailable. I’ve tried the cheaper 'basic' versions and they did absolutely nothing. This one actually hits the bloodstream and does its thing. If you want to stop feeling like a zombie and start feeling like an adult again, just buy the bottle. It’s a total necessity.
J**S
The Best Choice for L Methylfolate
I’ve gone through many other brands L Methylfolate since this is something I will always need because I have the genetic mutation where my body won’t break down folate and Opti-folate is hands down the best choice in my opinion. I’ve never had any issue with the product, I feel the price point is reasonable and the quality is the best I’ve come across.
L**Y
Best supplement for mental health
I bought this due to learning I have the mthfr gene mutation which my doctor described as me not being able to use folic acid properly so I need to take L-Methylfolate to be able to get the vitamins. I did some research and found that folic acid is linked to depression, which I have been living with for about 20 years in addition to ADHD. Being on ADHD and depression medicines worked for focus and not having the super low lows that can come with these struggles but with a big side effect. I wasn’t happy even when I should be, I could get things done but couldn’t relax, I could think but it was slower and for lack of a better way to explain, I lost my words. Speaking or writing in general was a mess. I would stop in the middle of a sentence to try and decider the word that I wanted to use but couldn’t find it. The meaning of what I was trying to say would be lost in my attempts to find the correct words or phrases and figure out how to pronounce them. Writing was chaos. As my job is writing all day long this was a hinderance to say the least. Sentences would be run on. I would rewrite a simple sentence or two 3-4 times and end up repeating myself or leaving out important information. Overall what would be written was messy and couldn’t flow well in reading. I started taking these in the 7.5 mg dose. Within HOURS I realized that I was writing more clearly. It hit me like a ton of bricks actually. I had written a message to a customer, about something that comes up often, and the wording that I used was beautiful. It was what I call writing pretty because the words flow together, I makes sense and the full meaning behind the words is evident while reading and without any need to think about what is meant. Easy to say, I was excited. I am still excited to be able to think and express myself well again. Even just a few days in I feel wonderful. My other half, who has been diagnosed with depression, and our daughter, who is showing signs of depression too, have started taking these too and showing that it is helping them too! I don’t believe in “cure alls” but fully believe that a lack of vitamins and nutrients impact our well being and mental health. If you have depression or just feeling low a lot, check with your doctor to see if you could be low. Should it be found you need extra folic acid, these are the way to go.
1**S
To help myself get the most out of my medications
I’ve tried several different brands of L- Methylfolate and these are the ones I came back to and stayed with. Finding that I have the MTHFR-5 gene mutation via genetic testing, my Dr. suggested L-Methylfoate to help my other medications work a little better, mainly geared, in this discussion, toward my antidepressants. I couldn’t believe there could be such a simple solution to medications not working as well for me as we’d like, but it has helped. I felt a small boost in my mood and in regards to my pain management medications several weeks after I first started them. I’ve switched brands and even discontinued them once or twice to see if I really felt a difference and came to the conclusion that the Carlyle brand serves me best. I was taking the 15 mg - the more the better, right? - and came down when my folate levels were found to be too high. I’d say they’re working:)
S**A
Honest Review
Great supplement. Easy to swallow, gentle on my stomach, and I can feel a noticeable boost in mood and energy.
Trustpilot
3 days ago
1 day ago