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🐕🦺 Elevate your pet’s skin health game — because they deserve vet-grade care!
Douxo S3 PYO Chlorhexidine Shampoo is a clinically proven, vet-recommended antiseptic shampoo designed to treat bacterial and yeast skin infections in dogs and cats. Enriched with 0.5% natural Ophytrium, it soothes and hydrates irritated skin while being free from soaps, sulfates, parabens, colorants, nanoparticles, and phthalates, ensuring gentle yet effective care.





















| ASIN | B0949RKDYC |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #473 in Pet Supplies ( See Top 100 in Pet Supplies ) #3 in Dog Shampoos |
| Brand | Douxo |
| Brand Name | Douxo |
| Customer Reviews | 4.7 out of 5 stars 8,436 Reviews |
| Included Components | Shampoo |
| Item Form | Shampoo |
| Item Type Name | Shampoos & Conditioners |
| Item Weight | 1.1 pounds |
| Liquid Volume | 500 ml |
| Manufacturer | Douxo S3 |
| Manufacturer Part Number | D98420E |
| Material Type Free | Soap Free, Sulfate Free, Paraben Free, Dye Free, Nanoparticle Free |
| Model Number | D98420E |
| Pet Type | Cat, Dog |
| Product Benefits | Anti-Fungal |
| Recommended Uses For Product | Irritated Skin,Moisturizing |
| Scent | coconut and vanilla |
| Scent Name | coconut and vanilla |
| Special Ingredients | chlorhexidine, ophytrium |
| Target Species | dog, cat |
| UPC | 850002593433 |
| Unit Count | 1 Count |
C**E
Best ever for yeasty shih tzu
As a professional groomer I can't recommend this product enough. In Dec we got a new Shih Tzu pup who was very yeasty. First thing we did is change her feed, and bathed her in every to my knowledge for yeast for the next 5 months, nothing worked and I mean nothing. As a groomer I didn't want her on the vicious cycle of steroids and antibiotics that only temporarily give her relief. After much research I took the 40.00 leap as a last ditch effect before letting the Vet medicate her. I kid you not the 1st bath and she was clearing up. You have to take your time and really work the product into the coat allowing to set for a bit before rinsing. I do 2 lathers letting each set for 10 mins. Rinse extra well. Today was her 3 bath in this amazing product. No itching, no yeasty musty smell and no itching during her dryer time. The smell is nice, pricy but a little goes a long way and worth every cent. I honestly need it in gallon size for my grooming room.
A**N
This product works!! Expensive but oh so worth it!🐶❤️🐶
My poor English bulldog Oakly was scratching so bad and we HAD to try this and do it quickly I ordered this after doing research and got it overnight , very fast delivery! After washing her , which lathered up very well we crossed our fingers and prayed it would help her, after about an hour we noticed the scratching was less thank God and after a few more hours past the scratching became very far and between , down to none! It worked!! Make sure when washing that you let it sit on your fur baby atleast 5 to 10 minutes before rinsing, that's where the magic happens! I'm so grateful for this product oh and did I mention the wonderful smell, it's not to strong, kinda vanilla scent. Will definitely buy again but use sparingly because it is expensive and the bottle is small but oh so worth it for your baby.🐶❤️🐶
S**Y
Amazing!
After many vet visits and different products used this is the only thing that helped my boo girl with her skin allergies. She smells better, hair is growing back, it’s a little brutal watching your dog shiver for the time you have to let it sit lathered on them but oh so worth it for a healthy pup. My dog looks like my dog again and she’s acting like herself too! Worked wonders for her. Leaves her soft and beautiful.
R**N
Great product
This works so good on my dog. It doesn’t smell bad either. Her coat is soft and shiny after and def helps with itching and skin issues.
T**A
Read for severe itchy/yeasty dog review
Anyone who suffers with an itchy, paw licking, hot spot suffering canine- read on. I have a dog who is seemingly allergic to air. His paws get so bad they bleed when he walks!! And at one point he scratched himself raw on his neck. So, this is a severe case. We have tried everything under the sun. Everything. So, I’d consider myself an expert at this point. Here is my honest review of the Douxo line: Shampoo: this is the best product in the line. I use once a week. Honestly, it works for about 2-3 days, then needs another go. That’s expensive for the small bottle and my big dog. It does remove corn chip odor. I try and leave it on 4-5 minutes in shower, but that can be tough with my dog who doesn't love showers. The smell is nice. It removed dandruff and cleared up his neck. I have considered soaking paws in this nightly, but not sure how that would go. Foam: in between washes we use the foam. This does seem to work- though it is messy to apply. I use mostly on legs, paws, and neck. It does keep down corn chip odor and seems to help redness. It is not a miracle cure. And, it's expensive for the extensive use. It helps, but does not cure/end the paw licking. Wipes: I use this extensively on paws each night. It is more cost affordable than the foam, but not as effective. Still it keeps his paws from bleeding. Does not handle the corn chip smell or stop bleeding- is more of a spot clean up. Now, anyone who deals with this knows this is just the outside. My guy is also on the K-9 probiotics. These seem to give him more energy, regular firm stools, and help his repetitive behavior. He does not mind taste at all. We have added Dogs are Human vitamins. All of this makes it bearable - it has not solved the problem. We are adding collagen next and I will update post if it helps significantly. The BIG PLUS of all of this is he is not on Aquapel, and we do not give him antihistamine daily anymore- which I feel good about. My dog is also OCD and the regimine here seems to have really helped with that. He does not chase lights nearly as much as he used to 8 out of 10 improvement. For all of this, I gave 4 stars because it is the best regimen of everything we have tried (which is everything) and has given him about a 6 out of 10 relief. Hope this helps! Best of luck to you!
B**Y
Try this before going to the vet for dandruff!
My dog is a 30lb collie/lab/Pekingese mix (so no idea on hair type) and she had this dandruff that wouldn't go away but she didn't smell like Fritos (yeast infection), so I took her to the vet and she recommended this shampoo. To wash her 3-4 times for 2 weeks and let her sit with it all soapy for 10-15 minutes. I've washed her now 3 times this week and let her sit soapy for 15 minutes; and I have seen a dramatic change. She has dramatically less to no more dandruff. So I would recommend to try this first before the expensive vet visit. The only thing I would note is that I have very sensitive skin on my hands and I would wash right after using this product but it did make my hands itch, so if you have sensitive hands you may want to use gloves.
K**D
Holy grail for old dog funk
My dog is elderly and she has that old dog funk that I can’t get rid of. I would bathe her and her stinky funk would come back the next day. I’ve tried other shampoos that are for dog odor, but none worked. I’ve even used a different brand that is antifungal/antibacterial that didn’t help. This one actually keeps her smelling good for at least one week. I feel pleased that I know if I bathe her with this, she will be good for at least a week. Granted, I wish she didnt stink but I’m so glad I bought this. Expensive but so worth it
C**E
Effective shampoo for dog yeast infections
This was an absolutely amazing shampoo to use on my dog when he had his yeast infections! It definitely stopped the itching & miraculously took away the yeast problems. It was a little pricey, but in the long run, it saved me any future huge vet bills!
A**X
Excelente para problemas de hongos y comezón
Mi perrita empezó a desarrollar un problema de dermatitis y se rascaba mucho, empezó a oler mucho a perro y el veterinario le diagnosticó levaduras. Buscando por recomendaciones encontré esta marca, y me gustó mucho. Huele rico, hace mucha espuma y deja el pelo suavecito. Aprobado para mi perrita 🐶
P**A
De vuelta a la normalidad
Excelente producto,un poco caro pero vale la pena. Mi perrita bulldog estaba realmente muy mal de la piel y ahora con los cuidados alimenticios y sus baños con este shampoo está de maravilla. Esperemos siga así
M**N
Excellent Shampoo
Exactly as described. Beautiful scent and a little amount goes a long way. Love it.
L**N
Bottle leaked and shampoo was on all the other purchases.
K**Y
Perfect for problematic skin.
Duoxo Pyo Shampoo has been a lifesaver for my dog. He has alopecia and very fragile skin, and at 16 years old, his aging skin requires extra care and attention. This shampoo was recommended by our veterinarian, and I am so grateful we found it. We use it for his weekly baths, and it helps keep his skin clean, fresh, and comfortable. I’ve noticed a significant improvement in his itching, flaking, and skin sores, and his skin looks much healthier overall. The formula is gentle enough for his sensitive skin while still being effective. The difference in his comfort level is remarkable. Without this shampoo, he would be much more uncomfortable and miserable. If you have a dog with sensitive, aging, or problem skin, I highly recommend giving this product a try. It has made a real difference in my senior dog’s quality of life.
Trustpilot
2 weeks ago
2 weeks ago