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๐พ Stay ahead of fleasโbecause your big buddy deserves the best!
Advantage II XL is a vet-recommended, topical flea treatment designed for dogs over 55 lbs. It kills fleas at all life stages within 12 hours and provides 30 days of waterproof, fragrance-free protection. Easy to apply with no prescription required, it safeguards your dog from discomfort and health risks associated with fleas, ensuring your large breed stays happy and itch-free all season long.














| ASIN | B004QBL9IQ |
| Active Ingredients | Imidacloprid, Pyriproxyfen |
| Age Range Description | 7 weeks and older |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #1,614 in Pet Supplies ( See Top 100 in Pet Supplies ) #14 in Dog Flea Drops |
| Brand | Advantage |
| Brand Name | Advantage |
| Customer Reviews | 4.5 out of 5 stars 6,805 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00724089203052, 00724089617743, 10724089366341 |
| Item Form | Topical |
| Item Type Name | Topical |
| Item Volume | 16 ml |
| Item Weight | 1.6 ounces |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 86336634 |
| Model Number | 81520305 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089617743 724089203052 |
| Unit Count | 4 Count |
| Volume | 16 ml |
J**K
Reliable protection for my girl!
โFinding an effective flea treatment for a large dog can be a challenge, but Advantage II has always been my go-to. This 4-month supply for dogs 55+ lbs is perfect for keeping my dog protected throughout the season. Itโs easy to apply, waterproof, and I love that it kills fleas at all life stagesโlarvae and eggs includedโso we don't have to deal with any re-infestations. My order was delivered right on time on May 8th, and it's such a relief to have peace of mind knowing he's covered. Highly recommend for any large breed owners!
E**S
Gene
Works for 30 days without entering your dogs blood stream. It stays in the fatty tissue. THEREFORE NOT TAXING YOUR DOGS VITAL ORGANS.
M**S
A Helpful Tool In Our Flea Control Regimen!
We have double coated, long haired, very furry large Northern Breed Mixed Dogs. Unfortunately, fleas are a year round problem here in the San Francisco Bay Area where we live ... Ugh! Advantage II Topical Flea Treatment & Prevention is an effective tool in our flea control regimen. - Easy to apply the topical drops on your dog's skin along the backbone. - Our dogs have never had any skin irritation or other negative reactions with this product. - The 6 pack is a terrific value. I highly recommend this product.
R**.
Worked for years, losing effectiveness over time
I have 9 cats and 1 corgi dog that weighs in at 30 pounds. I was looking for something that would be cost effective and safe for both cats and dogs, in the proper dose. My vet taught me how to dose the product out for the different weights of my animals and that has saved me a lot of money while keeping my fur family healthy. The chemical that is in this product started out working very well. Over the years it seems to be losing its effectiveness earlier each month. The fleas would start dying off and the animals would be comfortable all summer, with uninterrupted application. Now they will be back to itching after 2 weeks. In addition, some of the cats have developed lumps at the application site. I have a couple that are sensitive to the chemical and would foam at the mouth....we had to adjust the "standard" dose down. There is also the smell....it is all consuming and fills the whole house, lingers on your hands and furniture and leaves their coats greasy looking at the application site. Despite what sounds like negative aspects, the product worked for years and is better than being flea infested!! I am sad that it's loosing effect, so I have switched to a different product with a different chemical. Perhaps alternating chemical treatments from year to year would stop the fleas from building a resistance to one product??
S**S
Definitely doesn't kill ticks
So far I haven't noticed any fleas. But it may not be time for them yet.
H**H
Great product, great value- fleas are gone!
I've been using Advantage for flea control for several years, and Amazon is one of the best places to get it. You can't beat $10 a month for large dog flea protection. I also use one tube split into fifths (via syringe measurement) to give to my cats. Advantage II specifically is exactly the same product, in different dosages, for both dogs and cats. My 70-lb Lab gets a full 40 ml tube by herself, then the cats get 8 ml each and my brother-in-law's two ferrets get 4 ml each. I can cover 7 pets for $20 a month- a fantastic deal. The Advantage makes a noticeable difference in my pets' comfort- towards the end of the month, when it's wearing off, they begin to get itchy and uncomfortable. Once I reapply, that stops within a day or two, and they're happy and flea-free again all month. I have noticed that if our dog regularly gets into water (pool, beach, sprinklers), the Advantage wears off much quicker, despite claiming to be waterproof. That's understandable in a topical treatment, so we try to keep her out of water until the end of the application cycle, before a new treatment- then she gets to get wet to her heart's content! If you need to bathe your dog to kill fleas before applying, be sure to wait a day or two after the bath to give your dog's natural skin oils a chance to bounce back- it helps to distribute the medication. Be aware: this product is alcohol-based, and will evaporate quickly if left out in open air (we use a glass baby food jar to split the dosages in the syringe). It has also stripped the lacquer off the dining table when a few drops spilled while splitting doses, so try to avoid that too! Other than that, Advantage II is, in my opinion, the best topical flea control.
N**H
How to Use the "Extra Large Pack" to dose multiple dogs! Saves money on this great product!
I live in the American South, and my vets agree that Advantage works better than Frontline or any generic products. To get the most value for your money, I recommend buying the dosage for extra-large dogs and splitting it among smaller dogs. Save a small jar such as for pimentos or olives. Ask your pharmacist for a plastic dosing syringe (the kind for giving kids liquid medicine); they will likely give you one. I've attached a sample picture of the type of syringe you need. You need one without a needle that holds the amount of ML you will be using, based on the below guidelines. Take off your dog's collar to ensure it doesn't slide down onto where you will be putting the Advantage. Open a package of Advantage and pour it into the jar. Pull into the syringe the right amount for your dog's weight: 0.4ml = 0-10# 0.8ml = 11-20# 1.2ml = 21-30# 1.6ml = 31-40# 2.0ml = 41-50# 2.4ml = 51-60# 2.8ml = 61-70# 3.2ml = 71-80# You will put part of the Advantage on the dog's neck, and part of it in a few places down his back. Use your fingers to part the dog's hair on the back of his neck. (See package instructions on where to place the treatment.) Slowly depress the plunger onto the skin, NOT on top of the hair. Otherwise, it will drip off of the hair. Do several more spots down the dog's spine. Immediately give treats to keep them from shaking their heads around. I learned the hard way that, if your dog vigorously shakes, this product can take the paint off cabinets and the varnish off stainless steel!! I do the treatment outside and leave the dogs outside for an hour or so. Buying the largest size of Advantage and dosing several dogs with it can save a lot of money in the long run. Let's say your dog weighs 32 lbs, and you purchase the "Large dog for pets 21-55 lbs" and put the entire tube on him. You will be giving him 2.5 ML when he really only needs 1.6 ML. In a home with several dogs, this can add up! Of course, talk to your vet if you have questions. This is just how I do it at my house! I am not a vet. I plan to post a video showing how I use this method. **I have relied heavily on reviews for years, since I do most of my shopping online. I've finally starting trying to return the favor by writing reviews of products I love. I hope my review was helpful to you!**
D**Y
Gets the job done
It's hard to find an affordable, OTC flea repellant that applies monthly on the neck and WORKS. This stuff does the job. I have two 25 pound dogs and the small dog application is way smaller and ridiculously expensive. Our monthly budget is super tight, but I must take care of my animals, so I went looking for a cheaper way to get a good OTC flea repellant that works. This WORKS. For me. I can't guarantee it'll work for you, of course. I don't know you, I don't know your dog. Duh. Fleas are different all over the nation and some have developed immunity to this kind of repellant and some repellants just don't work. Disclaimer: I'm about to tell you what I do with this. If you decide to do the same, I take no responsibility for your results. I'm just saying this works for me. Ok, so I did some research on The Innernetz. I found out that if you get the extra large dog size, you get way more medicine for your money. It makes it cost way less per ml. I got this item. I got a little, airtight, really secure glass bottle, and a 1.0ml syringe. All from Amazon. The research I found said to use 1.2ml for a 25 pound dog. So at the beginning of every month, I open one extra large dog application, squirt it into the little glass jar, stick in the blunt syringe, and pull the plunger all the way, which is about 1.2ml. I then apply it on my dogs just as I would the small dog application. No fleas in our house. Thank GOD. Because once they get in, they're almost impossible to get rid of, and it's crazy-making. BTW, dusting diatomaceous earth and using an insect growth regulator are a good way to get rid of an infestation.
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