Glu-C, Sequencing Grade, 50μg
Product ID: 43700769
Description
- Cleaves at the C-Terminus of Either Aspartic or Glutamic Acid Residues
- Optimal activity at pH 4–9
- Ammonium and phosphate buffers can affect cleavage; see details in product information
- Suitable for in-solution digestion; not recommended for in-gel digestion
Glu-C, Sequencing Grade (S. aureus V8), is a serine protease that specifically cleaves at the C-terminus of either aspartic or glutamic acid residues. In ammonium bicarbonate and ammonium acetate the enzyme specificity is higher at the glutamic residues. In phosphate buffers cleavage occurs at the aspartic and glutamic residues. Glu-C activity is optimal in the pH range of 4.0-9.0. This sequencing grade enzyme can be used alone or in combination with other proteases to produce protein digests for peptide mapping applications. It is suitable for digestion reactions in solution.
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