I know it says to give on an empty stomach, but is it ok to hide the pill in a small piece of food? Not sure my dog would eat just the pill.

Yes! The packaging says “tablets should be given on an empty stomach; however, if needed they can be administered with a small amount of food or treat.” (The reason I took my Sheltie to the vet in the first place was because he suddenly stopped eating. After tests, my dog was prescribed this medication for his liver problems. But how do you feed pills to a dog that won’t eat anything, not even his treats or cheese? Well, the vet opened a can of pate’ CAT FOOD and surprisingly my dog ate it! The vet said cat food is normally too fatty to be healthy for dogs but they’ll eat it -even when they won’t eat anything else-because it’s like a super-juicy hamburger to them! The vet suggested putting the pill in a small ball of canned pate’ cat food, especially if your dog has no appetite. First, give a tiny ball of pate’ without a pill so they anticipate the flavor then give them a ball with the pill hidden in it while showing them there is more- tricking them into gulping down the pill-ball. Follow up with a tiny dab of cat food and you’re done for an hour when they can stop fasting and eat a meal. In my dog’s case, the meal was cat food pate’ for a few days, then soft-ish dog food smeared with cat food pate’, and now we just use the cat food to hide pills in.) Sorry for the long answer, hope it helps someone.

How large are the pills? I have a cat w/ liver failure & the pills from the vet are HUGE. Looking for an alternative asap. Thank You! :)

I give one for my 11 lbs. poodle which is the small one and a larger one for my 22 lbs. poodle. I gave up on the trauma of cramming it down their throat with a pill dispenser. I know direction say on an empty stomach; however, it is important they take the pills so I bought some human liver pate over in the deli meat section and I give the a tiny treat to trick them...about the size of a ballpoint pen end and then I wrap the pill in just enough liver that they wolf it down and then I give them that tiny bit to follow up. I know it sounds crazy but I watched a vet on youtube show how and it worked. The first little bit programs them for the larger piece which only covers the pill...they wolf it right down. I know it is working because the 22lbs. liver was so high it wouldn't even register on the scale. Follow up last week the liver blood work showed a dramatic drop to well below 300. Hope that helps.

Has anyones dog had any adverse reactions to this product? Ours did.

My dog had diarrhea, but it was from a change to raw food, not Denamarin. Once he had transitioned to entirely raw, diarrhea for two days straight. Once he was back on his canned food, he was fine, with normal poop. The real positives are that he has perked up, that he is hungry, and that some of the side effects from Adrenal Cushing's have improved: less water drinking, hair growing in thicker, less of a pot belly, and skin lesions have decreased. I am happy that he is improving and will continue with this.

Nutramax claims this product does not require a persciption (a dietary suppliment) but is only sold to licenseed vets?

No it is not only sold to vets, because my vet told me to go to Amazon to order this product

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Reviews

S**C

Good price, good product.

My vet recommended this for my dog. Shipping is fast and reliable and price is equal or cheaper than getting directly from the vet or from any pet store near me. It seems to of been pretty effective as her blood tests are improving! A bit of a large pill but I put it in soft food and she never notices.

5.02.2026

A**N

Really helped my 14-year old lab

My vet prescribed this for my 14 year old lab who had liver issues, which we discovered after a blood test. The vet said she was otherwise healthy, and could very well live another year if we got the liver stabilized. She gets a one daily pill now, and it has drastically improved her quality of life. You could tell before she was tired, sore, she never ran, struggled to get up some basic stairs and didn't like going for walks... after a few days on this, she was wagging her tail again, and even running and jumping which I hadn't seen her do in probably a year. She'll walk a mile or more with us now and seems happy, head up and tail wagging the entire time. It's made a big difference for her quality of life in her elder years.

17.12.2025

A**R

Liver enzymes back to normal

Helps my senior dogs’ liver enzymes. All 3 were elevated and now back in the normal range! A bit expensive but works to keep my girl healthy

30.12.2025

D**L

Helped my dog with his liver issues

25.01.2026

J**Y

Good supp that you wrap in a treat and give it to your pup

Overall this supplement works for my dog and isn't too big. I wrap it in a treat and our pup eats it every time. Haven't had any issues with vomitting or diarrhea.

20.01.2026

S**D

Nutramax Denamarin

Our veterinarian recommended my elderly dog take Denamarin as a supplement. She takes it on an empty stomach daily and seems to be doing very well. For my own convenience, I place a pill inside of a pill pocket and she thinks she’s getting a treat and that way I’m not stressing and neither is she about chewing a pill. The price was outrageous at the vet’s office, so I looked on Amazon and Voila, this is where I will purchase it from now on.

14.11.2025

J**R

Great product

Great product ! Cheaper on Snaxin than at the vet!

13.01.2026

P**K

Didn’t work for my dog

Recommended by my vet but didn’t improve the blood test.

11.02.2026

ASIN	B0BHKP6YLB
ASIN	B0BHKP6YLB
Age Range Description	All Life Stages
Best Sellers Rank	#925 in Pet Supplies ( See Top 100 in Pet Supplies ) #22 in Dog Supplements & Vitamins
Brand Name	Nutramax Laboratories
Breed Recommendation	Large Breeds
Color	white
Customer Reviews	4.6 4.6 out of 5 stars (1,274)
Date First Available	October 7, 2022
Date First Available	October 7, 2022
Directions	For dogs up to 12 lbs, 1 tablet per day. For cats up to 12 lbs, 1 tablet per day; for cats over 12 lbs one tablet twice daily. Tablets should be given on an empty stomach for optimal absorption. They may be given at least two hours after a meal or one hour before a meal.
Item Dimensions LxWxH	1.88 x 1.88 x 3.63 inches
Item Package Dimensions L x W x H	3.23 x 1.69 x 1.65 inches
Item Weight	2.08 ounces
Item model number	3000112
Item model number	3000112
Manufacturer	Nutramax Laboratories Veterinary Sciences, Inc.
Manufacturer	Nutramax Laboratories Veterinary Sciences, Inc.
Model Name	Denamarin Liver Health Supplement
Number of Items	1
Product Dimensions	1.88 x 1.88 x 3.63 inches; 2.08 ounces
Size	Bottle Large Dog (over 35 lbs)
Specific Uses for Product	Urinary
Target Audience Keyword	Dogs, dogs

Nutramax Denamarin for Large Dogs, Liver Health Supplement with S-adenosylmethionine (SAMe) plus Silybin, Liver Support for Dogs, Coated Tablets, 30 Count

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