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🌟 Wake up to younger, radiant skin — because aging gracefully is the new power move.
ISDIN Isdinceutics Retinal Advanced is a 50ml rejuvenating night serum formulated with retinaldehyde and melatonin. Clinically proven to reduce wrinkles by 43% in 4 weeks, it uses a dual-phase technology to maintain ingredient stability and is suitable for all skin types, including sensitive skin. This serum smooths skin texture, improves firmness, and enhances radiance while supporting natural overnight skin repair.
















| ASIN | B0CC9W3VWR |
| Brand | ISDIN |
| Brand Name | ISDIN |
| Customer Reviews | 4.4 out of 5 stars 215 Reviews |
| Item Volume | 1.7 Fluid Ounces |
| Manufacturer | ISDIN |
| Manufacturer Part Number | 690023835 |
| Product Benefits | Dermatologist Recommended |
| Recommended Uses For Product | Wrinkles |
| Skin Tone | All |
| Skin Type | All |
| Special Ingredients | Vitamin E |
| Target Use Body Part | Skin |
| Unit Count | 1.7 Fluid Ounces |
| Use for | Skin |
R**L
First Retinoid Product - so far so good!
I’ve never used retinal/retinol etc, so using this product is my very first attempt. I am 40+, fair skin, sensitive skin, dry skin, med/large pores, still prone to hormonal breakouts, some sun damage freckling, pretty deep 11s, and very minor wrinkles anywhere else. I started using this right around 2/1/24. It’s now 2 months of almost nightly use since (I’ve skipped a couple nights here or there just from schedule issues). I do use a full 2 pumps each time, every night, and I run the excess down my neck and upper chest to help with signs of aging there. I thought FOR SURE I would have bad peeling, redness, etc because I have sensitive skin and usually EVERYTHING makes me red or break out. But this hansy been bad at all! I started to think that might mean it’s a dud product, but I have been going thru “purge” for about 3-4 weeks. Not constant, but a couple of rounds of very agitated pimples. Moreso than I usually get, and I am used to have them every month with my cycle. So that makes me feel like it’s doing SOMETHING! I think I may be on the downward slope of the purge…. Hopefully. How does my skin feel or look? Well, it actually does feel more hydrated and softer than ever. I love that! It looks slightly more even tone (between the breakout areas when I’m having pimples and generally all over when I’m not having a breakout.) I also feel like I’m seeing a little more radiance or glow. Nothing miraculous, but just a little more shine and luster. I have not noticed a reduction in my deep 11s or my 2 very fine forehead lines. So far I’m happy. It’s such an expensive product I hate that you have to spend so much to find out if it works, but I feel like the signs I’m seeing now support continued use and expense. At 2 months, it looks to me like I might have 1 month of product left in the jar. For the price I paid, if it lasts 3 months, that’s about $62 a month ($744 a year!). I’ve never had an rx from a derm, so I’m not sure how that compares to prescription and office visit costs. I’m going to continue trying this for the full year. If I feel confident that I’m seeing results, I’ll do a cost comparison of actually getting on and maintaining a retinoid rx or just continuing this product. Will update!
M**E
I love it
Value for money, effectiveness, excellent texture.
H**A
Good product
Make my skin soft
A**R
Top skincare product
The best product!! Have been using for 9 months and have seen a significant improvement. My skin is more glowing and have seen a decrease in dark spots. Worth the price
J**A
Excelente
Excelente, redujo mis pecas y mantiene más firme mi piel y reduce los signos de envejecimiento prematuro
S**D
Works well for hyperpigmentation
This product works. I hate to say that it's worth the money. But I guess it is. I would purchase it again. I'm not done with my first bottle. But I had a little time of hormonal breakouts and after months of regular facials all of my flawless skin was wrecked by hormonal acne. In short order I have seen this product turn over that skin. Full disclaimer I am microneedling every 6 weeks. However I can say that this product has helped my skin remove a lot of the hyperpigmentation left by the hormonal acne. And I'm back to a really good place. I don't like that it's only a 3-month shelf life. That's even more concerning. Because I just microneedled and you have to not microneedle a couple days before and after. Nonetheless I'm sure I can use it before the 3 months is up. I have seen significant difference in my skin's turn over. I would suggest it. I give it four stars for the price and 3 month shelf life. However that's probably what makes it work because it works so well you have to use it within 3 months or the efficaciousness is compromised. I am chocolate complexioned and I will buy it again.
K**T
Excellent retinol
Looooooove what this ISDIN retinol does to my skin. I purchased it originally from a pharmacy overseas as a recommendation from the pharmacist. I wanted to have smoother skin. I purchased it again off Amazon when I ran out. Great product! Just a pea size amount at night and moisturizer afterwards.
M**A
Muy caro
Buen producto, pero está carisimo lo compre en USA pensando que eras barato y resulta que en México cuesta 45 dls vs 185 dls en USA
Trustpilot
4 days ago
2 weeks ago